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Allergy

Achieving Control through Aerobic Conditioning

IRB-HSR#: 12239

Category: Healthy Subject Studies

Primary Investigator: Susan Pollart, M.D., Co-Investigator: Kurt Elward, M.D.

Common Cold

IRB-HSR#: 12656

Category: Immunology/Infectious Diseases, Pulmonary/Respiratory, Healthy Subjects - Outpatient

Primary Investigator: Peter W. Heymann

Audiology (Children)

Children Needed for an Ear Study

IRB-HSR#: 13729

Category: Healthy Subjects - Outpatient

Primary Investigator: Hendley J. Owen

Otitis Media Study

IRB-HSR#: 13978

Category: Healthy Subjects - Outpatient

Primary Investigator: Birgit Winther, M.D.

Cancer

A Double-Blind Phase III Trial of Doxorubicin and Cyclophosphamide followed by Paclitaxel with Bevacizumab or Placebo in Patients with Lymph Node Positive and High Risk Lymph Node Negative Breast Cancer

IRB-HSR#: 13713

Category: Cancer (Oncology)

Primary Investigator: Christiana M. Brenin, M.D.

(08-PIR-05) A Multicenter, Open-Label, Phase 2 Study to Evaluate the Safety and Efficacy of NKTR-102 (PEG-Irinotecan) When Given on a Q14 Day or a Q21 Day Schedule in Patients with Metastatic Breast Cancer Whose Disease has Failed Prior Taxane-Based Treat

IRB-HSR#: 14126

Category: Cancer (Oncology), Women's Health

Primary Investigator: Christiana Brenin, M.D.

A Double-blind, Randomized, Placebo-controlled Phase III Study to Assess the Efficacy of recMAGE-A3 + AS15 ASCI as Adjuvant Therapy in Patients with MAGE-A3 Positive Resected Stage III Melanoma

IRB-HSR#: 14686

Category: Cancer (Oncology)

Primary Investigator: Craig L. Slingluff, M.D.

A Multicenter, Open-Label, Phase 2 Study to Evaluate the Safety and Efficacy of NKTR-102 (PEG-Irinotecan) When Given on a Q14 Day or a Q21 Day Schedule in Patients with Metastatic or Unresectable Locally Advanced Platinum-Resistant Ovarian Cancer

IRB-HSR#: 14130

Category: Cancer (Oncology), Obstetrics/Gynecology

Primary Investigator: Linda Duska, M.D.

A Phase 1 Dose Finding Study of the Safety and Pharmacokinetics of XL184 Administered Orally in Combination with Temozolomide and Radiation Therapy in the First Line Treatment of Subjects with Glioblastoma

IRB-HSR#: 14459

Category: Cancer

Primary Investigator: David Schiff, M.D.

A Phase 1 Study of UCN-01 in Combination with Irinotecan in Resistant Solid Tumor Malignancies (Part I) and in Triple Negative (ER-negative, PgR-negative, HER-2 not-amplified) Recurrent Breast Cancers (Part II)

IRB-HSR#: 13296

Category: Cancer (Oncology)

Primary Investigator: Paula Fracasso, M.D., Ph.D.

A Phase 2 Study of CCI-779 in Combination with Bevacizumab in Stage III or IV Melanoma

IRB-HSR#: 12471

Category: Cancer (Oncology), Dermatology/Plastic Surgery

Primary Investigator: Craig L. Slingluff, M.D.

A Phase 2 Study of XL184 in Subjects with Progressive or Recurrent Glioblastoma Multiforme in First or Second Relapse

IRB-HSR#: 14185

Category: Neurology, Cancer

Primary Investigator: David Schiff, M.D.

A Phase 2, Randomized, Open-label Study of Bosutinib Administered in Combination With Exemestane Versus Exemestane Alone as Second Line Therapy in Postmenopausal Women With Locally Advanced or Metastatic ER+/PgR+/ErbB2- Breast Cancer

IRB-HSR#: 14674

Category: Cancer (Oncology)

Primary Investigator: Christiana Brenin, M.D.

A Phase 3, Randomized, Open-Label Study of Neratinib Versus Lapatinib Plus Capecitabine for the Treatment of ErbB-2-Positive Locally Advanced or Metastatic Breast Cancer

IRB-HSR#: 14626

Category: Cancer (Oncology), Women's Health

Primary Investigator: Christiana Brenin, M.D.

A Phase I Feasibility Trial IP Cisplatin and IV Paclitaxel on Day One Followed by IP Paclitaxel on Day 8 Every 21 Days as Front-line Treatment of Ovarian, Fallopian Tube and Primary Peritoneal Carcinoma

IRB-HSR#: 14232

Category: Cancer (Oncology), Obstetrics/Gynecology

Primary Investigator: Linda Duska, M.D.

A Phase I/ II Trial of Sorafenib and CCI-779 in Patients with Recurrent Glioblastoma

IRB-HSR#: 12421

Category: Neurology, Cancer

Primary Investigator: David Schiff, M.D.

A Phase II Evaluation of Preoperative Chemoradiotherapy Utiizing Intensity Modulated Radiation Therapy (IMRT) in Combination with Capecitabine and Oxaliplatin for Patients with Locally Advanced Rectal Cancer (RTOG 0822)

IRB-HSR#: 13851

Category: Cancer (Oncology)

Primary Investigator: Tyvin Rich

A Phase II/III Study Comparing Acupuncture-like Transcutaneous Electrical Nerve Stimulation (ALTENS) Versus Pilocarpine in Treating Early Radiation-Induced Xerostomia (RTOG 0537)

IRB-HSR#: 13990

Category: Cancer (Oncology)

Primary Investigator: Paul Read, M.D.

A Phase III Randomized Trial of Lobectomy versus Sublobar Resection

IRB-HSR#: 13622

Category: Cancer (Oncology), Surgery

Primary Investigator: Benjamin Kozower, M.D.

A Phase III Trial Evaluating the Role of Ovarian Function Suppression and the Role of Exemestane as Adjuvant Therapies for Premenopausal Women with Endocrine Responsive Breast Cancer IBCSG 24-02 (SOFT)

IRB-HSR#: 13760

Category: Cancer (Oncology)

Primary Investigator: Christiana Brenin, M.D.

A Phase III Trial of Irinotecan/5-FU/Leucovorin or Oxaliplatin/5-FU/Leucovorin with Bevacizumab, or Cetuximab (C225), or with the Combination of Bevacizumab and Cetuximab for Patients with Untreated Metastic Adenocarcinoma or the Colon or Rectum

IRB-HSR#: 14308

Category: Cancer (Oncology), Hematology

Primary Investigator: Geoffrey R. Weiss, M.D.

A Phase III Trial of Pelvic Radiation Therapy Versus Vaginal Cuff Brachytherapy Followed by Paclitaxel/Carboplatin in Patients with High-Risk, Early Stage Endometrial Cancer

IRB-HSR#: 14354

Category: Cancer (Oncology)

Primary Investigator: Susan Modesitt, M.D.

A Randomized Phase 2 Open-Label Study of IMC-A12, as a Single Agent or in Combination With Cetuximab, in Patients With Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck and Disease Progression on Prior Platinum-Based Chemotherapy

IRB-HSR#: 14088

Category: Cancer (Oncology)

Primary Investigator: Christopher Thomas, M.D.

A Randomized Phase III Study of Conventional Whole Breast Irradiation (WBI) Versus Partial Breast Irradiation (PBI) for Women with Stage O, 1, or II Breast Cancer

IRB-HSR#: 11904

Category: Cancer (Oncology)

Primary Investigator: Paul Read, M.D.

A Randomized Phase III trial of Maintenance Chemotherapy Comparing 12, Monthly Cycles of Single Agent Paclitaxel or Xyotax (CT-2103) (IND #70177) Versus No Treatment Until Documented Relapse in Women With Advanced Ovarian or Primary Peritoneal Cancer Who Achieve A Complete Clinical Response to Primary Platinum/Taxane Chemotherapy.

IRB-HSR#: 12615

Category: Obstetrics/Gynecology

Primary Investigator: Susan Modesitt, M.D.

ASSURE: Adjuvant Sorafenib or Sunitinib for Unfavorable Renal Carcinoma

IRB-HSR#: 13763

Category: Cancer (Oncology)

Primary Investigator: Christopher Thomas, M.D.

Adults with Cutaneous or Subcutaneous Metastatic Melanoma (Stage IIIB-IV) wanted for research study

IRB-HSR#: 14215

Category: Cancer (Oncology)

Primary Investigator: Craig L. Slingluff, M.D.

An Exploratory Pharmacogenomic Study of Neoadjuvant Cetuximab Followed by Cisplatin, Radiotherapy, and Cetuximab in Women with Newly Diagnosed Locally Advanced or Metastatic Cervical Carcinoma,(CA225243)

IRB-HSR#: 13748

Category: Cancer (Oncology)

Primary Investigator: Linda Duska, M.D.

An Intergroup Phase III Randomized Controlled Trial Comparing Melphalan, Prednisone and Thalidomide Versus Melphalan, Prednisone and Lenalidomide in Newly Diagnosed Myeloma Patients Who Are Not Candidates for High-Dose Therapy

IRB-HSR#: 13576

Category: Cancer (Oncology), Hematology

Primary Investigator: John Densmore, M.D.

Assessing Shared Decisions in Cancer Screening

IRB-HSR#: 13989

Category: Cancer (Oncology)

Primary Investigator: Kerry Kilbridge

BIBW 2992 With or Without Temozolomide in the Treatment of Patients with Recurrent Malignant Glioma

IRB-HSR#: 13747

Category: Cancer (Oncology)

Primary Investigator: David Schiff, M.D.

Bladder Tissue Bank (DXT002)

IRB-HSR#: 9179

Category: Cancer (Oncology)

Primary Investigator: Dan Theodorescu

Dalteparin Sodium Injection (FRAGMIN®), Multicenter, Open Label, Single-arm, Long Term (52 weeks) Study for Understanding Safety and Efficacy in Subjects with Malignancies and Symptomatic Venous Thromboembolism

IRB-HSR#: 14288

Category: Cancer (Oncology), Hematology

Primary Investigator: B. Gail Macik, M.D.

Early Stage Lung Cancer Patients wanted for research study.

IRB-HSR#: 14447

Category: Cancer (Oncology), Surgery

Primary Investigator: David R. Jones, M.D.

Health Insurance, Labor Supply, and Health

IRB-HSR#: 13938

Category: Cancer (Oncology), Surgery

Primary Investigator: David Brenin, M.D.

Men and Non-pregnant Women ages 18 or Older, with Newly Diagnosed Stage III or IV Squamous Cell Head and Neck Cancer Needed for a Research Study

IRB-HSR#: 14049

Category: Cancer (Oncology)

Primary Investigator: Paul Read, M.D.

Men and Women age 18 or Older Wanted for Brain Tumor Study

Cancer

IRB-HSR#: 13988

Category: Neurology, Cancer

Primary Investigator: David Schiff, M.D.

Men and Women, Age 18 or Older, Who Have Been Recently Diagnosed with Esophageal Cancer for a Research Study

IRB-HSR#: 14034

Category: Cancer (Oncology)

Primary Investigator: Tyvin Rich

Patients with Recurrent Brain Tumor Needed for Study at UVA

IRB-HSR#: 13467

Category: Neurology, Cancer

Primary Investigator: David Schiff, M.D.

Phase I Study of Induction Therapy with VELCADE and Vorinostat in Patients with Surgically Resectable Non-small Cell Lung Cancer

IRB-HSR#: 12472

Category: Cancer (Oncology), Surgery

Primary Investigator: David R. Jones, M.D.

Phase I/II Study of ZD6474 (ZactimaTM) with Radiation Therapy and Concomitant and Adjuvant Temozolomide in Patients with Newly-Diagnosed Glioblastoma

IRB-HSR#: 13291

Category: Cancer (Oncology)

Primary Investigator: David Schiff, M.D.

Phase II Double Blind Randomized Trial Evaluating The Biologic Effect of Levonorgestrel on the Ovarian Epithelium in Women at High Risk for Ovarian Cancer

IRB-HSR#: 13755

Category: Cancer (Oncology)

Primary Investigator: Susan C. Modesitt, M.D.

Phase II Trial of Observation for Low-Risk Meningiomas and of Radiotherapy for Intermediate and High-Risk Meningiomas (RTOG 0539)

IRB-HSR#: 14722

Category: Cancer (Oncology)

Primary Investigator: James Larner, M.D.

Phase II Trial of Sunitinib (SU011248) in Patients with Recurrent or Inoperable Meningioma

IRB-HSR#: 13605

Category: Cancer

Primary Investigator: David Schiff, M.D.

Phase II/III Study of Image-Guided Radiosurgery/SBRT for Localized Spine Metastasis (RTOG 0631)

IRB-HSR#: 14718

Category: Cancer (Oncology), Pain Management

Primary Investigator: Paul Read, M.D.

Phase III Study of Radiation Therapy with or without Temozolomide for Symptomatic or Progressive Low-Grade Gliomas

IRB-HSR#: 14665

Category: Neurology, Cancer

Primary Investigator: David Schiff, M.D.

Phase III Trial of Bisphosphonates as Adjuvant Therapy for Primary Breast Cancer

IRB-HSR#: 13759

Category: Cancer (Oncology)

Primary Investigator: Christiana Brenin, M.D.

Program for the assessment of clinical cancer tests (PACCT-1): Trial assigning individualized options for treatment: The TAILORx Trial

IRB-HSR#: 12657

Category: Cancer (Oncology)

Primary Investigator: Anneke Schroen, M.D.

Randomized Phase III Study Comparing 5-FU, Leucovorin, and Oxaliplatin vs. 5-FU, Leucovorin, Oxaliplatin and Bevacizumab in Patients w/Stage II Colon Cancer at High Risk for Recurrence to Determine Prospectively the Prognostic Value of Molecular Markers

IRB-HSR#: 13711

Category: Cancer (Oncology)

Primary Investigator: Geoffrey R. Weiss, M.D.

Randomized Phase III Trial Comparing the Frequency of Major Erythroid Response (MER) to Treatment with Lenalidomide (Revlimid®) Alone and in Combination with Epoetin Alfa (Procrit®) in Subjects with Low-or Intermediate-1 Risk MDS and Symptomatic Anemia

IRB-HSR#: 14434

Category: Cancer (Oncology), Hematology

Primary Investigator: Michael E. Williams, M.D.

Randomized, Open-Label, Phase 3 Trial of Erlotinib Alone or in Combination with CP-751,871 in Patients with Advanced Non-Small Cell Lung Cancer of Non-Adenocarcinoma Histology

IRB-HSR#: 14339

Category: Cancer (Oncology), Pulmonary/Respiratory

Primary Investigator: Thomas J. Harris, M.D.

Recurrent or Persistent Cervical Cancer

IRB-HSR#: 14351

Category: Cancer (Oncology)

Primary Investigator: Susan Modesitt, M.D.

Reflective Exercise (RE) or Acupuncture for Fatigue in Breast Cancer Patients Receiving Radiotherapy

IRB-HSR#: 13958

Category: Cancer (Oncology)

Primary Investigator: Tyvin Rich

Seeking Adults 18 and Older with Advanced Indolent Non-Hodgkins Lymphoma or Mantle Cell Lymphoma Who Have Never Received Treatment for Lymphoma

IRB-HSR#: 14518

Category: Cancer (Oncology)

Primary Investigator: John Densmore, M.D.

Sonorheometry Repeatability and Sensitivity

IRB-HSR#: 12600

Category: Healthy Subject Studies

Primary Investigator: William F. Walker, M.D.

Standard-dose versus High-dose Radiotherapy for Treatment of Non-Small Cell Lung Cancer

IRB-HSR#: 13516

Category: Cancer (Oncology)

Primary Investigator: James Larner, M.D.

Study VEG108844, a Study of Pazopanib versus Sunitinib in the Treatment of Subjects with Locally Advanced and/or Metastatic Renal Cell Carcinoma

IRB-HSR#: 14087

Category: Cancer (Oncology)

Primary Investigator: Christopher Thomas, M.D.

Women Ages 18 and Above with Platinum Sensitive, Recurrent Ovarian, Fallopian Tube, or Primary Peritoneal Cancer Needed for Research Study

IRB-HSR#: 13501

Category: Obstetrics/Gynecology

Primary Investigator: Susan Modesitt, M.D.

Women Who Plan to Have Their Ovaries Removed Sought for Research Study

IRB-HSR#: 13230

Category: Cancer (Oncology), Obstetrics/Gynecology

Primary Investigator: Susan Modesitt, M.D.

Cancer (Children)

A Phase III Randomized Trial of Gemtuzumab Ozogamicin (Mylotarg(r) Combined with Conventional Chemotherapy for De Novo Acute Myeloid Leukemia (AML) in Children, Adolescents, and Young Adults

IRB-HSR#: 13315

Category: Cancer (Oncology), Pediatrics

Primary Investigator: Kimberly Dunsmore, M.D.

A Randomized Trial of the European and American Osteosarcoma Study Group to Optimize Treatment Strategies for Resectable Osteosarcoma Based on Histological Response to Pre-operative Chemotherapy: A Phase III Intergroup Study

IRB-HSR#: 12547

Category: Cancer (Oncology), Pediatrics

Primary Investigator: Kimberly Dunsmore, M.D.

Children aged 1-10 with ALL Sought for Research Study

IRB-HSR#: 12087

Category: Cancer (Oncology), Pediatrics

Primary Investigator: Kimberly Dunsmore, M.D.

Children over 10 years of age with ALL Leukemia sought for research study

IRB-HSR#: 11847

Category: Cancer (Oncology), Pediatrics

Primary Investigator: Kimberly Dunsmore, M.D.

Clinical Trial for Children and Adolescents with Intermediate-risk Neuroblastoma

IRB-HSR#: 13633

Category: Cancer (Oncology), Pediatrics

Primary Investigator: Kimberly Dunsmore, M.D.

Clinical Trial for Patient with Acute Lymphoblastic Leukemia

IRB-HSR#: 14391

Category: Cancer (Oncology), Pediatrics

Primary Investigator: Kimberly Dunsmore, M.D.

Clinical Trials for Patients With Intermediate-risk, Newly Diagnosed Rhabdomyosarcoma

IRB-HSR#: 13667

Category: Cancer (Oncology), Pediatrics

Primary Investigator: Kimberly Dunsmore, M.D.

Infants With an Adrenal Tumor for a Research Study

IRB-HSR#: 11920

Category: Cancer (Oncology)

Primary Investigator: Eugene McGahren, M.D.

Phase III Randomized Study of Chimeric Antibody 14.18 (Ch14.18) in High Risk Neuroblastoma Following Myeloablative Therapy and Autologous Stem Cell Rescue

IRB-HSR#: 14593

Category: Cancer (Oncology), Pediatrics

Primary Investigator: Kimberly Dunsmore, M.D.

Risk-Based Treatment for Non-Rhabdomyosarcoma Soft Tissue Sarcomas (NRSTS) in Patients Under 30 Years of Age COG#: ARST0332

IRB-HSR#: 14624

Category: Cancer (Oncology), Pediatrics

Primary Investigator: Kimberly Dunsmore, M.D.

Treatment for Very Low, Low and Standard Risk Favorable Histology Wilms Tumor

IRB-HSR#: 13671

Category: Cancer (Oncology)

Primary Investigator: Kimberly Dunsmore, M.D.

Treatment of Newly Diagnosed Higher Risk Favorable Histology Wilms Tumors

IRB-HSR#: 14379

Category: Cancer (Oncology), Pediatrics

Primary Investigator: Kimberly Dunsmore, M.D.

Continuum Home Health

No clinical trials available at this time.

Dentistry

No clinical trials available at this time.

Dentistry (Children)

No clinical trials available at this time.

Dermatology

No clinical trials available at this time.

Developmental and Behavioral (Children)

Asthma and Breathlessness in School Age Children

IRB-HSR#: 12280

Category: Musculoskeletal/Sports Medicine

Primary Investigator: Thomas A Platts-Mills

Diabetes and Endocrinology (Children)

Adolescent Hormone Study

IRB-HSR#: 10504

Category: Healthy Subjects - Inpatient

Primary Investigator: Christopher McCartney, M.D.

Assessment of nocturnal secretion of progesterone, testosterone, estradiol, LH, and FSH secretion during pubertal maturation in adolescent girls with and without exposure to elevated androgens - JCM014

IRB-HSR#: 9868

Category: Healthy Subjects - Outpatient

Primary Investigator: John C Marshall, M.D.

Effect of Metformin on Sensitivity of the GnRH Pulse Generator to Suppression by Estradiol and Progesterone in Hyperandrogenic Adolescent Girls (JCM025)

IRB-HSR#: 13789

Category: Endocrinology, Obesity

Primary Investigator: John C Marshall, MD

Evaluation of Adrenal Androgen Production in Normal and Obese Girls After Suppression and Stimulation (JCM022)

IRB-HSR#: 12702

Category: Endocrinology, Healthy Subjects - Inpatient

Primary Investigator: John Marshall, M.D.

Infants With an Adrenal Tumor for a Research Study

IRB-HSR#: 11920

Category: Cancer (Oncology)

Primary Investigator: Eugene McGahren, M.D.

Reproductive Hormone Study

IRB-HSR#: 13552

Category: Healthy Subjects - Inpatient

Primary Investigator: Christopher McCartney, M.D.

Reproductive Hormone Study

IRB-HSR#: 13950

Category: Healthy Subjects - Inpatient

Primary Investigator: Christopher McCartney, M.D.

S-Nitrosylation & Inflammation in Obstructive Sleep Apnea

IRB-HSR#: 13441

Category: Endocrinology

Primary Investigator: Mark DeBoer

Time Course of Waking vs. Sleep-Associated LH Pulse Frequency Suppression in Response to Progesterone in Late Pubertal Girls with and Without Hyperandrogenemia (CRM003)

IRB-HSR#: 13717

Category: Healthy Subjects - Inpatient, Pediatrics

Primary Investigator: Christopher McCartney, M.D.

Diabetes & Metabolism

Determination of the Role of Dihydrotestosterone in Mediating Relative GnRH Pulse Generator Resistance to Ovarian Steroid Feedback in Adults with PCOS (JCM018)

IRB-HSR#: 10842

Category: Endocrinology, Healthy Subjects - Inpatient

Primary Investigator: Christopher McCartney M.D.

Determine the Temporal Relationships Between Pulsatile Acyl- and Des-Acyl Ghrelin Secretion and Plasma Concentrations of Insulin, Cortisol, and Growth Hormone in Healthy Lean Insulin-Sensitive and Obese Insulin-Resistant Adults (MOT105)

IRB-HSR#: 13376

Category: Endocrinology, Healthy Subject Studies, Healthy Subjects - Inpatient

Primary Investigator: Michael O. Thorner, M.D.

Effect of age on insulin mediated regulation of ghrelin

IRB-HSR#: 12223

Category: Healthy Subject Studies

Primary Investigator: Nass Ralf, M.D.

Healthy Women Wanted for Breast-Feeding Study

IRB-HSR#: 12441

Category: Healthy Subjects - Outpatient

Primary Investigator: Sue Brown, M.D.

Influence of Hyperandrogenemia on the Sleep-Associated Slowing of Follicular LH Frequency in Adult Polycystic Ovary Syndrome (CRM004)

IRB-HSR#: 14067

Category: Endocrinology, Healthy Subjects - Inpatient

Primary Investigator: Christopher McCartney M.D.

Insulin mediated forearm muscle microvascular recruitment and insulin uptake in healthy subjects (EJB039)

IRB-HSR#: 12127

Category: Healthy Subject Studies

Primary Investigator: Eugene Barrett, M.D., Ph.D.

PYR-210: A Randomized, Double-Blind, Placebo-Controlled, Multi-Center, Phase 2b Study to Evaluate the Safety and Efficacy of Pyridorin (Pyridoxamine Dihydrochloride) in Patients with Nephropathy Due to Type 2 Diabetes

IRB-HSR#: 13884

Category: Endocrinology, Nephrology (Kidney)

Primary Investigator: Bolton W. Kline, M.D.

Pharmacogenetics of Metformin Action in PCOS (WSE035)

IRB-HSR#: 14041

Category: Endocrinology, Women's Health

Primary Investigator: William S. Evans, M.D.

Promoting "Stories of Success": Enhancing Diabetes Self-Care (SWU001)

IRB-HSR#: 14478

Category: Healthy Subject Studies

Primary Investigator: Sharon Utz, Ph.D., R.N.

Reproductive Hormone Studies

IRB-HSR#: 13368

Category: Women's Health, Healthy Subjects - Inpatient

Primary Investigator: Christopher McCartney M.D.

S-Nitrosylation & Inflammation in Obstructive Sleep Apnea

IRB-HSR#: 13441

Category: Endocrinology

Primary Investigator: Mark DeBoer

The impact of glucose (peripheral or luminal) and/or insulin on the short-term regulation of ghrelin

IRB-HSR#: 12561

Category: Healthy Subject Studies

Primary Investigator: Ralf Nass M.D., P.I.

The impact of insulin on the short term regulation of ghrelin.(RMN003)

IRB-HSR#: 13109

Category: Healthy Subject Studies

Primary Investigator: Ralf Nass M.D., P.I.

UVA Islet Cell Transplantion in Patients with Type I Diabetes (KBL004)

IRB-HSR#: 12839

Category: Endocrinology, Nephrology (Kidney)

Primary Investigator: Kenneth Brayman, M.D., Ph.D.

Urinary Angiotensinogen Excretion in Normal Subjects and Patients with Type II Diabetes Mellitus (RMC032)

IRB-HSR#: 12940

Category: Endocrinology , Nephrology (Kidney)

Primary Investigator: Robert M. Carey, M.D.

Digestive (Children)

No clinical trials available at this time.

Digestive Health

A Phase 2b, Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel-group Study to Evaluate the Efficacy and Safety of Ustekinumab Therapy in Subjects with Moderately to Severely Active Crohn's Disease Previously Treated with TNF Antagonist

IRB-HSR#: 14449

Category: Gastroenterology/Hepatology

Primary Investigator: Behm Brian, M.D.

A Phase 3, Randomized, Placebo-Controlled, Blinded, Multicenter Study of the Induction and Maintenance of Clinical Response and Remission by Vedolizumab (MLN0002) in Patients with Moderate to Severe Ulcerative Colitis

IRB-HSR#: 14493

Category: Gastroenterology/Hepatology

Primary Investigator: Behm Brian, M.D.

Effect of Metformin on Sensitivity of the GnRH Pulse Generator to Suppression by Estradiol and Progesterone in Hyperandrogenic Adolescent Girls (JCM025)

IRB-HSR#: 13789

Category: Endocrinology, Obesity

Primary Investigator: John C Marshall, MD

Non-Invasive Imaging of GI Inflammation Using Microbubble Contrast Enhanced Ultrasonography (CEU)

IRB-HSR#: 11971

Category: Gastroenterology/Hepatology

Primary Investigator: Behm Brian, M.D.

Pravastatin Therapy in Patients with Active Crohn's Disease: A Pilot Study

IRB-HSR#: 11453

Category: Gastroenterology/Hepatology

Primary Investigator: Behm Brian, M.D.

Eye Care

No clinical trials available at this time.

Eye Care (Children)

No clinical trials available at this time.

General Pediatrics (Children)

No clinical trials available at this time.

Genetics (Children)

No clinical trials available at this time.

Head and Neck (Children)

Effectiveness of Surface Cleaners in Reducing Transfer of Human Rhinovirus (HRV) to Fingertips through Activities of Daily Life (ADL)

IRB-HSR#: 13829

Category: Otolaryngology

Primary Investigator: Birgit Winther, M.D.

Ear, Nose and Throat

Effectiveness of Surface Cleaners in Reducing Transfer of Human Rhinovirus (HRV) to Fingertips through Activities of Daily Life (ADL)

IRB-HSR#: 13829

Category: Otolaryngology

Primary Investigator: Birgit Winther, M.D.

Otitis Media Study

IRB-HSR#: 13978

Category: Healthy Subjects - Outpatient

Primary Investigator: Birgit Winther, M.D.

Heart

Acute Venous Thrombosis: Thrombus Removal With Adjunctive Catheter-Directed Thrombolysis (The ATTRACT Trial)

IRB-HSR#: 14442

Category: Cardiology/Vascular

Primary Investigator: John F. Angle

Cardiovascular Outcomes in Renal Atheroscerotic Lesions: The CORAL Trial

IRB-HSR#: 11950

Category: Nephrology (Kidney)

Primary Investigator: John F. Angle

Evaluation of the GORE TAG® Thoracic Endoprosthesis 45 mm for the Primary Treatment of Aneurysms of the Descending Thoracic Aorta (Protocol Number: TAG 06-02)

IRB-HSR#: 12894

Category: Cardiology/Vascular , Surgery

Primary Investigator: Alan Matsumoto, M.D.

ReCardioversion in Afib Study

IRB-HSR#: 13790

Category: Heart Center

Primary Investigator: John Ferguson

THE PARTNER TRIAL: Placement of Aortic Transcatheter Valves Trial With Cohort B as Continued Access

IRB-HSR#: 14096

Category: Cardiology/Vascular

Primary Investigator: Irving L. Kron, M.D.

Heart (Children)

Acute Venous Thrombosis: Thrombus Removal With Adjunctive Catheter-Directed Thrombolysis (The ATTRACT Trial)

IRB-HSR#: 14442

Category: Cardiology/Vascular

Primary Investigator: John F. Angle

Immunology and Rheumatology (Children)

No clinical trials available at this time.

Infectious Disease (Children)

No clinical trials available at this time.

Infectious Diseases

No clinical trials available at this time.

Kidney

Cardiovascular Outcomes in Renal Atheroscerotic Lesions: The CORAL Trial

IRB-HSR#: 11950

Category: Nephrology (Kidney)

Primary Investigator: John F. Angle

Do You Have Stage 4 or Stage 5 Kidney Disease?

IRB-HSR#: 13684

Category: Nephrology (Kidney)

Primary Investigator: Bolton W. Kline, M.D.

PYR-210: A Randomized, Double-Blind, Placebo-Controlled, Multi-Center, Phase 2b Study to Evaluate the Safety and Efficacy of Pyridorin (Pyridoxamine Dihydrochloride) in Patients with Nephropathy Due to Type 2 Diabetes

IRB-HSR#: 13884

Category: Endocrinology, Nephrology (Kidney)

Primary Investigator: Bolton W. Kline, M.D.

UVA Islet Cell Transplantion in Patients with Type I Diabetes (KBL004)

IRB-HSR#: 12839

Category: Endocrinology, Nephrology (Kidney)

Primary Investigator: Kenneth Brayman, M.D., Ph.D.

Urinary Angiotensinogen Excretion in Normal Subjects and Patients with Type II Diabetes Mellitus (RMC032)

IRB-HSR#: 12940

Category: Endocrinology , Nephrology (Kidney)

Primary Investigator: Robert M. Carey, M.D.

Kidney Care (Children)

Infants With an Adrenal Tumor for a Research Study

IRB-HSR#: 11920

Category: Cancer (Oncology)

Primary Investigator: Eugene McGahren, M.D.

Urinary Markers of Upper Urinary Tract Obstruction

IRB-HSR#: 11734

Category: Healthy Subjects - Outpatient

Primary Investigator: Jonathan Roth, M.D.

Neonatology (Children)

No clinical trials available at this time.

Neurology and Neurosurgery (Children)

No clinical trials available at this time.

Neurosciences

A Historical-controlled, Multicenter, Double-blind, Randomized Trial to Assess the Efficacy and Safety of Conversion to Lacosamide 400mg/day Monotherapy in Subjects with Partial-onset Seizures.

IRB-HSR#: 13381

Category: Neurology

Primary Investigator: Nathan B. Fountain

A Mulitcenter Prospective Study of Neurological Recovery as a Factor of Time to Decompression of Cervical Spinal Cord Injuries with Spinal Cord Compression

IRB-HSR#: 9717

Category: Neurosurgery

Primary Investigator: Chris Shaffrey

A Multicenter, Double-Blind, Parallel Group, Placebo Controlled Study of Creatine in Subjects with Treated Parkinson's Disease (PD). Long-term Study - 1 (LS-1)

IRB-HSR#: 12781

Category: Neurosciences

Primary Investigator: G. Frederick Wooten, Jr. M.D.

A Phase 2 Study of XL184 in Subjects with Progressive or Recurrent Glioblastoma Multiforme in First or Second Relapse

IRB-HSR#: 14185

Category: Neurology, Cancer

Primary Investigator: David Schiff, M.D.

A Phase I/ II Trial of Sorafenib and CCI-779 in Patients with Recurrent Glioblastoma

IRB-HSR#: 12421

Category: Neurology, Cancer

Primary Investigator: David Schiff, M.D.

A Phase III, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Efficacy and Safety Trial of Bapineuzumab (AAB-001, ELN115727) in Patients with Mild to Moderate Alzheimer's Disease Who are Apolipoprotein E 4 Non-Carriers (DSG001)

IRB-HSR#: 13853

Category: Neurology

Primary Investigator: David S Geldmacher, M.D.

Are you a family member of someone with memory loss?

IRB-HSR#: 14290

Category: Neurosciences

Primary Investigator: Karen Rose

CONCERT: A Phase 3 Multicenter, Randomized, Placebo-Controlled, Double-Blind Twelve-Month Safety and Efficacy Study Evaluating Dimebon in Patients with Mild-To-Moderate Alzheimer's Disease on Donepezil

IRB-HSR#: 14280

Category: Neurosciences

Primary Investigator: David S Geldmacher, M.D.

Cognitive Stability Index Validation Study

IRB-HSR#: 14221

Category: Neurology

Primary Investigator: Donna K. Broshek

Cooperative Huntington's Disease Observational Research Trial (COHORT)

IRB-HSR#: 12184

Category: Neurosciences

Primary Investigator: M. B. Harrison, M.D.

Cranial Electrical Stimulation Effects on Symptoms in Persons with Fibromyalgia

IRB-HSR#: 14203

Category: Rheumatology

Primary Investigator: Ann Gill Taylor, Ed.D, R.N.

GORE HELEX Septal Occluder and Antiplatelet Medical Management for Reduction of Recurrent Stroke or Imaging-Confirmed TIA in Patients with Patent Foramen Ovale (PFO)- The GORE REDUCE Study

IRB-HSR#: 14012

Category: Neurology

Primary Investigator: Nina Solenski

Genetic Risk Factors for Medication-Related Hemorrhagic Stroke

IRB-HSR#: 11535

Category: Neurology

Primary Investigator: Bradford Worrall, M.D.

Impulse Control Disorders and Parkinson's Disease: the Effect of Dopamine Therapy on Decision-Making and Response Inhibition

IRB-HSR#: 14451

Category: Neurology

Primary Investigator: Daniel O. Claassen, M.D.

Insulin Resistance Intervention after Stroke (IRIS) Trial

IRB-HSR#: 11520

Category: Neurology

Primary Investigator: Karen C. Johnston, M.D., M.S.c.

Men and Women age 18 or Older Wanted for Brain Tumor Study

Cancer

IRB-HSR#: 13988

Category: Neurology, Cancer

Primary Investigator: David Schiff, M.D.

Neural correlates of pretense

IRB-HSR#: 14432

Category: Neurology

Primary Investigator: James P. Morris

Novel Pharmacotherapy for Dual Dependence

IRB-HSR#: 11620

Category: Healthy Subjects - Inpatient

Primary Investigator: Johnson Bankole, M.D.

Patients with Recurrent Brain Tumor Needed for Study at UVA

IRB-HSR#: 13467

Category: Neurology, Cancer

Primary Investigator: David Schiff, M.D.

Phase III Study of Radiation Therapy with or without Temozolomide for Symptomatic or Progressive Low-Grade Gliomas

IRB-HSR#: 14665

Category: Neurology, Cancer

Primary Investigator: David Schiff, M.D.

Primary Progressive Multiple Sclerosis research study.

IRB-HSR#: 14115

Category: Neurology

Primary Investigator: Myla Goldman, M.D.

Reducing Alcohol Exposed Pregnancy Risk

IRB-HSR#: 14460

Category: Psychiatry/Psychology, Women's Health, Healthy Subjects - Outpatient

Primary Investigator: Karen Ingersoll, Ph.D.

Siblings With Ischemic Stroke Study (SWISS)

IRB-HSR#: 8953

Category: Neurology

Primary Investigator: Bradford B. Worrall

Subcortical contributions to imitation

IRB-HSR#: 14510

Category: Neurology

Primary Investigator: James P. Morris

THE EPIDEMIOLOGY, PROCESS, AND OUTCOMES OF SPINE TRAUMA: A MULTCENTER PROSPECTIVE ANALYSIS

IRB-HSR#: 12337

Category: Neurosurgery

Primary Investigator: Chris Shaffrey

The Effect of Parkinson's Disease on Event-Related Brain Potentials Linked to Response Selection and Inhibition

IRB-HSR#: 14141

Category: Healthy Subject Studies

Primary Investigator: Scott Wylie, Ph.D.

UVA Health System and the Social Neuroscience Lab in the Psychology Department seeks MEN Ages 18 - 45 for Research Study

IRB-HSR#: 14570

Category: Psychiatry/Psychology

Primary Investigator: James Morris, Ph.D.

Nutrition (Children)

No clinical trials available at this time.

Orthopaedics

Adolescents Ages 10-15 with Idiopathic Scoliosis for a Research Study

IRB-HSR#: 12688

Category: Musculoskeletal/Sports Medicine

Primary Investigator: Mark F. Abel

Adults with Low Back Pain for Exercise Study

IRB-HSR#: 14046

Category: Musculoskeletal/Sports Medicine

Primary Investigator: Susan A. Saliba, Ph.D., ATC, PT

Children and Adolescents Ages 8 Years and up for a Research Study

IRB-HSR#: 12955

Category: Musculoskeletal/Sports Medicine

Primary Investigator: Bradford C Bennett

Do You Have an Ankle Sprain?

IRB-HSR#: 13960

Category: Healthy Subject Studies

Primary Investigator: Jay Hertel, Ph.D., A.T.C., FNATA

Men and Women Ages 16-65 who Have Had an Injury or Reconstruction to the Anterior Cruciate Ligament Needed for a Research Study

IRB-HSR#: 13691

Category: Musculoskeletal/Sports Medicine

Primary Investigator: Joseph Hart, Ph.D, ATC

Men and Women ages 18 to 55 who have Recently Torn a Knee Ligament and have Thigh Muscle Weakness needed for a Research Study

IRB-HSR#: 13398

Category: Musculoskeletal/Sports Medicine

Primary Investigator: Joseph Hart, Ph.D, ATC

Modeling and Simulation of the Vertical Climber

IRB-HSR#: 14287

Category: Musculoskeletal/Sports Medicine

Primary Investigator: Silvia Blemker,

Patients with Lumbar Spinal Stenosis Needed for Research Study

IRB-HSR#: 13852

Category: Musculoskeletal/Sports Medicine

Primary Investigator: Robert P. Wilder, M.D.

Prospective Study of Deformity Management and Pulmonary Function in Early-Onset Scoliosis: A Prospective Multi-Center Study

IRB-HSR#: 12778

Category: Musculoskeletal/Sports Medicine , Pediatrics

Primary Investigator: Mark F. Abel

Seeking Adults 18-40 with a History of Knee Injury and/or Surgery for a Research Study

IRB-HSR#: 13648

Category: Musculoskeletal/Sports Medicine

Primary Investigator: Christopher D. Ingersoll

Spectrum of Disability with Chronic Ankle Instability

IRB-HSR#: 14010

Category: Healthy Subject Studies

Primary Investigator: Jay Hertel, Ph.D., A.T.C., FNATA

Study for Adults with Painful Osteoarthritis of the Shoulder

IRB-HSR#: 12633

Category: Musculoskeletal/Sports Medicine

Primary Investigator: David R. Diduch

The Effect of Surgery on Sagittal Spino-Pelvic Measures of Balance in Spondylolisthesis and its Relation to the Clinical Outcome

IRB-HSR#: 12861

Category: Musculoskeletal/Sports Medicine, Pediatrics

Primary Investigator: Mark F. Abel, M.D.

The Relationship Between Trunk Neuromuscular Control and Running Mechanics Following Cycling in Triathletes

IRB-HSR#: 14723

Category: Musculoskeletal/Sports Medicine

Primary Investigator: Joseph Hart, Ph.D., ATC

The Value of Sagittal Spino-Pelvic Measures of Balance to Predict the Natural History in Developmental Spondylolysis and Spondylolisthesis

IRB-HSR#: 12857

Category: Musculoskeletal/Sports Medicine, Pediatrics

Primary Investigator: Mark F. Abel

Volunteers 15 - 65 With or Without Unstable Ankles for a Muscle Activation Study

IRB-HSR#: 14179

Category: Musculoskeletal/Sports Medicine

Primary Investigator: Christopher D Ingersoll

Orthopaedics (Children)

Accrual of Bone Mineral in Children with Cerebral Palsy

IRB-HSR#: 13503

Category: Pediatrics

Primary Investigator: Christine M. Houlihan

Adolescents Ages 10-15 with Idiopathic Scoliosis for a Research Study

IRB-HSR#: 12688

Category: Musculoskeletal/Sports Medicine

Primary Investigator: Mark F. Abel

Children and Adolescents Ages 8 Years and up for a Research Study

IRB-HSR#: 12955

Category: Musculoskeletal/Sports Medicine

Primary Investigator: Bradford C Bennett

Do You Have an Ankle Sprain?

IRB-HSR#: 13960

Category: Healthy Subject Studies

Primary Investigator: Jay Hertel, Ph.D., A.T.C., FNATA

Prospective Pediatric Scoliosis Study

IRB-HSR#: 11691

Category: Musculoskeletal/Sports Medicine , Pediatrics

Primary Investigator: Mark F. Abel, M.D.

Prospective Study of Deformity Management and Pulmonary Function in Early-Onset Scoliosis: A Prospective Multi-Center Study

IRB-HSR#: 12778

Category: Musculoskeletal/Sports Medicine , Pediatrics

Primary Investigator: Mark F. Abel

The Effect of Surgery on Sagittal Spino-Pelvic Measures of Balance in Spondylolisthesis and its Relation to the Clinical Outcome

IRB-HSR#: 12861

Category: Musculoskeletal/Sports Medicine, Pediatrics

Primary Investigator: Mark F. Abel, M.D.

The Value of Sagittal Spino-Pelvic Measures of Balance to Predict the Natural History in Developmental Spondylolysis and Spondylolisthesis

IRB-HSR#: 12857

Category: Musculoskeletal/Sports Medicine, Pediatrics

Primary Investigator: Mark F. Abel

Palliative Care

No clinical trials available at this time.

Pituitary

Influence of Hyperandrogenemia on the Sleep-Associated Slowing of Follicular LH Frequency in Adult Polycystic Ovary Syndrome (CRM004)

IRB-HSR#: 14067

Category: Endocrinology, Healthy Subjects - Inpatient

Primary Investigator: Christopher McCartney M.D.

Plastic Surgery

A Phase 2 Study of CCI-779 in Combination with Bevacizumab in Stage III or IV Melanoma

IRB-HSR#: 12471

Category: Cancer (Oncology), Dermatology/Plastic Surgery

Primary Investigator: Craig L. Slingluff, M.D.

A Prospective, Two-center, Randomized, Crossover Clinical Investigation of Marathon® and Cavilon to Treat Peri-Wound Maceration in Subjects with Venous Leg Ulcers

IRB-HSR#: 14671

Category: Healthy Subject Studies

Primary Investigator: George T. Rodeheaver

Dust Mite, Cockroach & Cat Allergens in Houses/Asthma

IRB-HSR#: 2383

Category: Dermatology/Plastic Surgery

Primary Investigator: Thomas A Platts-Mills,

Plastic Surgery (Children)

No clinical trials available at this time.

Primary Care

No clinical trials available at this time.

Psychiatry

A Gene by Pharmacotherapy Interaction on Alcohol-elicited Craving and Sensitivity to the Acute Effects of Alcohol.

IRB-HSR#: 13464

Category: Psychiatry/Psychology

Primary Investigator: Heather M. Haughey, Ph.D.

A PHASE 2, DOUBLE-BLIND, PLACEBO CONTROLLED TRIAL TO ASSESS THE EFFICACY OF LEVETIRACETAM EXTENDED RELEASE IN VERY HEAVY DRINKERS

IRB-HSR#: 14453

Category: Psychiatry/Psychology

Primary Investigator: Bankole Johnson, M.D.

A Phase II, Randomized, Double-Blind, Placebo-Controlled, Flexible-Dose Study to Assess the Safety, Tolerability and Efficacy of RG2417 (Uridine) in the Treatment of Bipolar I Depression

IRB-HSR#: 14654

Category: Psychiatry/Psychology

Primary Investigator: Anita H. Clayton

A Phase III, Randomized, Double-Blind, Placebo-Controlled, Multi-Center Study of the Safety and Efficacy of Libigel® for the Treatment of Hypoactive Sexual Desire Disorder in Surgically Menopausal Women

IRB-HSR#: 13134

Category: Obstetrics/Gynecology, Psychiatry/Psychology, Women's Health

Primary Investigator: Anita H. Clayton, M.D.

Are you 50 or older and suffering from lack of sexual desire?

IRB-HSR#: 13557

Category: Psychiatry/Psychology

Primary Investigator: Anita H. Clayton

Combined Pharmacotherapies for Alcoholism/Genetic Variations and Treatment Response Among Alcoholics

IRB-HSR#: 12790

Category: Psychiatry/Psychology

Primary Investigator: Bankole Johnson, M.D.

Combining Medications for the Treatment of Alcohol Dependence: An Inpatient Preliminary Study (BAJ003)

IRB-HSR#: 13521

Category: Psychiatry/Psychology

Primary Investigator: Bankole Johnson, M.D.

Dose Response of Mirtazapine to Methamphetamine Induced Interest, Mood Elevation, and Reward

IRB-HSR#: 13222

Category: Pharmacology/Toxicology

Primary Investigator: Marzani-Nissen Gabrielle,

Healthy Gay and Lesbian Couples are Needed for a Research Study

IRB-HSR#: 12984

Category: Psychiatry/Psychology

Primary Investigator: James A. Coan, M.D.

Lab Trials to Develop Medications for Cocaine Dependence--Study 1(BAJ002)

IRB-HSR#: 12350

Category: Psychiatry/Psychology

Primary Investigator: Bankole Johnson, M.D.

Medication Development for Cocaine Dependence

IRB-HSR#: 11578

Category: Psychiatry/Psychology

Primary Investigator: Bankole Johnson, M.D.

Medications Development for the Treatment of Cannabis Related Disorders (HMH001)

IRB-HSR#: 14392

Category: Psychiatry/Psychology

Primary Investigator: Heather M. Haughey

Novel Pharmacotherapy for Dual Dependence

IRB-HSR#: 11620

Category: Healthy Subjects - Inpatient

Primary Investigator: Johnson Bankole, M.D.

Ondansetron for the Treatment of Heavy Drinking among Emerging Adults

IRB-HSR#: 13610

Category: Psychiatry/Psychology

Primary Investigator: Bankole Johnson, M.D.

Perspectives on Relaxation Techniques: A Structured Interview for Caregivers of Cognitively Impaired Persons

IRB-HSR#: 14414

Category: Psychiatry/Psychology, Healthy Subject Studies

Primary Investigator: Kim Innes, M.D.

Reducing Alcohol Exposed Pregnancy Risk

IRB-HSR#: 14460

Category: Psychiatry/Psychology, Women's Health, Healthy Subjects - Outpatient

Primary Investigator: Karen Ingersoll, Ph.D.

Supplementation of Antidepressants with Fatty Acid Therapy (Sad Fat)

IRB-HSR#: 14503

Category: Psychiatry/Psychology

Primary Investigator: Anita H. Clayton

UVA Health System and the Social Neuroscience Lab in the Psychology Department seeks MEN Ages 18 - 45 for Research Study

IRB-HSR#: 14570

Category: Psychiatry/Psychology

Primary Investigator: James Morris, Ph.D.

UVA Researchers Seek Voluteers for Womens Health Study

IRB-HSR#: 12794

Category: Psychiatry/Psychology

Primary Investigator: Karen Ingersoll, Ph.D.

Young Adult Driving Study

IRB-HSR#: 14500

Category: Healthy Subjects - Outpatient

Primary Investigator: Richard L. Merkel, M.D.

Psychiatry (Children)

No clinical trials available at this time.

Pulmonary & Respiratory Care

A Phase II Study in Patients with Asthma to Assess the Safety and Immunogenicity of an Unadjuvanted Novartis H1N1 Influenza Vaccine Administered at Two Dose Levels

IRB-HSR#: 14578

Category: Pulmonary/Respiratory

Primary Investigator: William G. Teague

A Prospective, Randmomized, Controlled Multi-center Clinical Trial to Evaluate the Safety and Effeciveness of the IBV Valve System for the Treatment of Severe Emphysema (JDT003)

IRB-HSR#: 12648

Category: Pulmonary/Respiratory

Primary Investigator: Jonathon D. Truwit

ARTEMIS: A Phase 3, Randomized, Double Blind, Placebo Controlled, Multi Center, Parallel Group, Event Driven Study to Evaluate the Efficacy and Safety of Ambrisentan in Subjects with Early Idiopathic Pulmonary Fibrosis (IPF)

IRB-HSR#: 14169

Category: Pulmonary/Respiratory

Primary Investigator: George Verghese, M.D.

Biology of Cytokines and 5-LO in the Pathogenesis of COPD

IRB-HSR#: 11928

Category: Pulmonary/Respiratory

Primary Investigator: Yun Michael Shim, M.D.

CNS Effects of Inhaled Xenon

IRB-HSR#: 14396

Category: Pulmonary/Respiratory

Primary Investigator: Talissa Altes, M.D.

Common Cold

IRB-HSR#: 12656

Category: Immunology/Infectious Diseases, Pulmonary/Respiratory, Healthy Subjects - Outpatient

Primary Investigator: Peter W. Heymann

Hyperpolarized Helium-3 MR Lung Imaging Findings in Asthmatics

IRB-HSR#: 8559

Category: Pulmonary/Respiratory

Primary Investigator: Eduard E. de Lange

Hyperpolarized Xenon-129 MR imaging of the Lung

IRB-HSR#: 13740

Category: Pulmonary/Respiratory

Primary Investigator: Talissa Altes, M.D.

Mechanisms and Treatment of Sleep-Disordered Breathing in Chronic Obstructive Pulmonary Disease (CDB001)

IRB-HSR#: 13855

Category: Pulmonary/Respiratory

Primary Investigator: Cynthia D. Brown, M.D.

People With Obstructive Sleep-Disordered Breathing (SDB) Generate High-Frequency Sounds When Inspiratory Effort is High as Measured by Esophageal Pressure

IRB-HSR#: 11486

Category: Pulmonary/Respiratory

Primary Investigator: Christopher M. Rembold, M.D.

Standard-dose versus High-dose Radiotherapy for Treatment of Non-Small Cell Lung Cancer

IRB-HSR#: 13516

Category: Cancer (Oncology)

Primary Investigator: James Larner, M.D.

Rehabilitation

The Relationship Between Hepcidin Levels and Menstrual Cycle Phase (SAS003)The Relationship Between Hepcidin Levels and Menstrual Cycle Phase (SAS003)

IRB-HSR#: 13053

Category: Healthy Subject Studies

Primary Investigator: Susan Saliba, Ph.D.

Rehabilitation (Children)

No clinical trials available at this time.

Respiratory and Allergy Care (Children)

No clinical trials available at this time.

Speech Language Pathology (Children)

No clinical trials available at this time.

Teen Health (Children)

Adolescent Hormone Study

IRB-HSR#: 10504

Category: Healthy Subjects - Inpatient

Primary Investigator: Christopher McCartney, M.D.

Adolescent Hormone Study

IRB-HSR#: 13502

Category: Healthy Subjects - Inpatient

Primary Investigator: John C Marshall, M.D.

Adolescent Hormone Study

IRB-HSR#: 8588

Category: Healthy Subjects - Outpatient

Primary Investigator: John C Marshall, M.D.

Assessment of nocturnal secretion of progesterone, testosterone, estradiol, LH, and FSH secretion during pubertal maturation in adolescent girls with and without exposure to elevated androgens - JCM014

IRB-HSR#: 9868

Category: Healthy Subjects - Outpatient

Primary Investigator: John C Marshall, M.D.

Reproductive Hormone Studies

IRB-HSR#: 13660

Category: Healthy Subjects - Inpatient

Primary Investigator: John C Marshall, M.D.

Reproductive Hormone Study

IRB-HSR#: 13552

Category: Healthy Subjects - Inpatient

Primary Investigator: Christopher McCartney, M.D.

Reproductive Hormone Study

IRB-HSR#: 13950

Category: Healthy Subjects - Inpatient

Primary Investigator: Christopher McCartney, M.D.

Reproductive Hormones Study

IRB-HSR#: 14100

Category: Healthy Subjects - Inpatient

Primary Investigator: John C Marshall, M.D.

Time Course of Waking vs. Sleep-Associated LH Pulse Frequency Suppression in Response to Progesterone in Late Pubertal Girls with and Without Hyperandrogenemia (CRM003)

IRB-HSR#: 13717

Category: Healthy Subjects - Inpatient, Pediatrics

Primary Investigator: Christopher McCartney, M.D.

Transplantation

Adults Undergoing Liver Transplant Wanted for Tissue Donation Study

IRB-HSR#: 11644

Category: Surgery

Primary Investigator: Timothy M. Schmitt

UVA Islet Cell Transplantion in Patients with Type I Diabetes (KBL004)

IRB-HSR#: 12839

Category: Endocrinology, Nephrology (Kidney)

Primary Investigator: Kenneth Brayman, M.D., Ph.D.

Urology

A multi-center, randomized, placebo-controlled clinical trial comparing fesoterodine to placebo in women diagnosed with urge urinary incontinence by the 3 Incontinence Questions (3IQ).

IRB-HSR#: 14023

Category: Women's Health

Primary Investigator: JoAnn V. Pinkerton, M.D.

Urology (Children)

Urinary Markers of Upper Urinary Tract Obstruction

IRB-HSR#: 11734

Category: Healthy Subjects - Outpatient

Primary Investigator: Jonathan Roth, M.D.

Vascular

A Prospective, Two-center, Randomized, Crossover Clinical Investigation of Marathon® and Cavilon to Treat Peri-Wound Maceration in Subjects with Venous Leg Ulcers

IRB-HSR#: 14671

Category: Healthy Subject Studies

Primary Investigator: George T. Rodeheaver

A Safety and Efficacy Trial Evaluating the Use of Apixaban for the Extended Treatment of Deep Vein Thrombosis and Pulmonary Embolism (CV 185057)

IRB-HSR#: 13883

Category: Cardiology/Vascular

Primary Investigator: B. Gail Macik

Acute Venous Thrombosis: Thrombus Removal With Adjunctive Catheter-Directed Thrombolysis (The ATTRACT Trial)

IRB-HSR#: 14442

Category: Cardiology/Vascular

Primary Investigator: John F. Angle

Cardiovascular Outcomes in Renal Atheroscerotic Lesions: The CORAL Trial

IRB-HSR#: 11950

Category: Nephrology (Kidney)

Primary Investigator: John F. Angle

Evaluation of Outcomes Following Mitral Valve Repair/Replacement in Severe Chronic Ischemic Mitral Regurgitation

IRB-HSR#: 13874

Category: Surgery

Primary Investigator: Irving L. Kron, M.D.

Evaluation of the GORE TAG® Thoracic Endoprosthesis 45 mm for the Primary Treatment of Aneurysms of the Descending Thoracic Aorta (Protocol Number: TAG 06-02)

IRB-HSR#: 12894

Category: Cardiology/Vascular , Surgery

Primary Investigator: Alan Matsumoto, M.D.

THE PARTNER TRIAL: Placement of Aortic Transcatheter Valves Trial With Cohort B as Continued Access

IRB-HSR#: 14096

Category: Cardiology/Vascular

Primary Investigator: Irving L. Kron, M.D.

Women's Health

(08-PIR-05) A Multicenter, Open-Label, Phase 2 Study to Evaluate the Safety and Efficacy of NKTR-102 (PEG-Irinotecan) When Given on a Q14 Day or a Q21 Day Schedule in Patients with Metastatic Breast Cancer Whose Disease has Failed Prior Taxane-Based Treat

IRB-HSR#: 14126

Category: Cancer (Oncology), Women's Health

Primary Investigator: Christiana Brenin, M.D.

A Multicenter, Open-Label, Phase 2 Study to Evaluate the Safety and Efficacy of NKTR-102 (PEG-Irinotecan) When Given on a Q14 Day or a Q21 Day Schedule in Patients with Metastatic or Unresectable Locally Advanced Platinum-Resistant Ovarian Cancer

IRB-HSR#: 14130

Category: Cancer (Oncology), Obstetrics/Gynecology

Primary Investigator: Linda Duska, M.D.

A Phase 3, Randomized, Open-Label Study of Neratinib Versus Lapatinib Plus Capecitabine for the Treatment of ErbB-2-Positive Locally Advanced or Metastatic Breast Cancer

IRB-HSR#: 14626

Category: Cancer (Oncology), Women's Health

Primary Investigator: Christiana Brenin, M.D.

A Phase I Feasibility Trial IP Cisplatin and IV Paclitaxel on Day One Followed by IP Paclitaxel on Day 8 Every 21 Days as Front-line Treatment of Ovarian, Fallopian Tube and Primary Peritoneal Carcinoma

IRB-HSR#: 14232

Category: Cancer (Oncology), Obstetrics/Gynecology

Primary Investigator: Linda Duska, M.D.

A Phase III, Randomized, Double-Blind, Placebo-Controlled, Multi-Center Study of the Safety and Efficacy of Libigel® for the Treatment of Hypoactive Sexual Desire Disorder in Surgically Menopausal Women

IRB-HSR#: 13134

Category: Obstetrics/Gynecology, Psychiatry/Psychology, Women's Health

Primary Investigator: Anita H. Clayton, M.D.

A Randomized Phase III trial of Maintenance Chemotherapy Comparing 12, Monthly Cycles of Single Agent Paclitaxel or Xyotax (CT-2103) (IND #70177) Versus No Treatment Until Documented Relapse in Women With Advanced Ovarian or Primary Peritoneal Cancer Who Achieve A Complete Clinical Response to Primary Platinum/Taxane Chemotherapy.

IRB-HSR#: 12615

Category: Obstetrics/Gynecology

Primary Investigator: Susan Modesitt, M.D.

A multi-center, randomized, placebo-controlled clinical trial comparing fesoterodine to placebo in women diagnosed with urge urinary incontinence by the 3 Incontinence Questions (3IQ).

IRB-HSR#: 14023

Category: Women's Health

Primary Investigator: JoAnn V. Pinkerton, M.D.

Adolescent Hormone Study

IRB-HSR#: 10504

Category: Healthy Subjects - Inpatient

Primary Investigator: Christopher McCartney, M.D.

Adolescent Hormone Study

IRB-HSR#: 13502

Category: Healthy Subjects - Inpatient

Primary Investigator: John C Marshall, M.D.

Adolescent Hormone Study

IRB-HSR#: 8588

Category: Healthy Subjects - Outpatient

Primary Investigator: John C Marshall, M.D.

Assessment of nocturnal secretion of progesterone, testosterone, estradiol, LH, and FSH secretion during pubertal maturation in adolescent girls with and without exposure to elevated androgens - JCM014

IRB-HSR#: 9868

Category: Healthy Subjects - Outpatient

Primary Investigator: John C Marshall, M.D.

Formula Switching for Infants

IRB-HSR#: 14281

Category: Obstetrics/Gynecology

Primary Investigator: James Sutphen

Genes that Account for Variation in Mammographic Breast Density

IRB-HSR#: 13372

Category: Women's Health

Primary Investigator: Jennifer Harvey, M.D.

Healthy Women Wanted for Breast-Feeding Study

IRB-HSR#: 12441

Category: Healthy Subjects - Outpatient

Primary Investigator: Sue Brown, M.D.

Healthy Women ages 21-40 Experiencing Infertility Needed for Research Study

IRB-HSR#: 14556

Category: Obstetrics/Gynecology

Primary Investigator: Alan H Matsumoto, M.D.

Novel Systems for Molecular Breast Imaging

IRB-HSR#: 8825

Category: Women's Health

Primary Investigator: Mark B. Williams

Pharmacogenetics of Metformin Action in PCOS (WSE035)

IRB-HSR#: 14041

Category: Endocrinology, Women's Health

Primary Investigator: William S. Evans, M.D.

Phase II Double Blind Randomized Trial Evaluating The Biologic Effect of Levonorgestrel on the Ovarian Epithelium in Women at High Risk for Ovarian Cancer

IRB-HSR#: 13755

Category: Cancer (Oncology)

Primary Investigator: Susan C. Modesitt, M.D.

Reducing Alcohol Exposed Pregnancy Risk

IRB-HSR#: 14460

Category: Psychiatry/Psychology, Women's Health, Healthy Subjects - Outpatient

Primary Investigator: Karen Ingersoll, Ph.D.

Reproductive Hormone Studies

IRB-HSR#: 13368

Category: Women's Health, Healthy Subjects - Inpatient

Primary Investigator: Christopher McCartney M.D.

Reproductive Hormone Studies

IRB-HSR#: 13660

Category: Healthy Subjects - Inpatient

Primary Investigator: John C Marshall, M.D.

Reproductive Hormone Study

IRB-HSR#: 13552

Category: Healthy Subjects - Inpatient

Primary Investigator: Christopher McCartney, M.D.

Reproductive Hormone Study

IRB-HSR#: 13950

Category: Healthy Subjects - Inpatient

Primary Investigator: Christopher McCartney, M.D.

Reproductive Hormones Study

IRB-HSR#: 14100

Category: Healthy Subjects - Inpatient

Primary Investigator: John C Marshall, M.D.

Research Study of Sexually Active Women

IRB-HSR#: 11959

Category: Women's Health

Primary Investigator: Barbara Parker, Ph.D. FAAN

The Effect of Aerobic Exercise Training on Endothelial Function in African American and Caucasian Women (ALW018)

IRB-HSR#: 13252

Category: Healthy Subjects - Outpatient

Primary Investigator: Arthur Weltman, Ph.D.

The Influence Of Acupuncture On Reproductive Hormones And Ovulation (LMP001)

IRB-HSR#: 12045

Category: Obstetrics/Gynecology

Primary Investigator: Lisa Pastore

The Relationship Between Hepcidin Levels and Menstrual Cycle Phase (SAS003)The Relationship Between Hepcidin Levels and Menstrual Cycle Phase (SAS003)

IRB-HSR#: 13053

Category: Healthy Subject Studies

Primary Investigator: Susan Saliba, Ph.D.

Time Course of Waking vs. Sleep-Associated LH Pulse Frequency Suppression in Response to Progesterone in Late Pubertal Girls with and Without Hyperandrogenemia (CRM003)

IRB-HSR#: 13717

Category: Healthy Subjects - Inpatient, Pediatrics

Primary Investigator: Christopher McCartney, M.D.

UVA Researchers Seek Voluteers for Womens Health Study

IRB-HSR#: 12794

Category: Psychiatry/Psychology

Primary Investigator: Karen Ingersoll, Ph.D.

Women Ages 18 and Above with Platinum Sensitive, Recurrent Ovarian, Fallopian Tube, or Primary Peritoneal Cancer Needed for Research Study

IRB-HSR#: 13501

Category: Obstetrics/Gynecology

Primary Investigator: Susan Modesitt, M.D.

Women Who Plan to Have Their Ovaries Removed Sought for Research Study

IRB-HSR#: 13230

Category: Cancer (Oncology), Obstetrics/Gynecology

Primary Investigator: Susan Modesitt, M.D.