Browse Clinical Trials

To find a clinical trial, browse by the medical services below.

Allergy

Achieving Control through Aerobic Conditioning

IRB-HSR#: 12239

Category: Healthy Subject Studies

Primary Investigator: Susan Pollart, M.D., Co-Investigator: Kurt Elward, M.D.

Common Cold

IRB-HSR#: 12656

Category: Immunology/Infectious Diseases, Pulmonary/Respiratory, Healthy Subjects - Outpatient

Primary Investigator: Peter W. Heymann

Audiology (Children)

Children Needed for an Ear Study

IRB-HSR#: 13729

Category: Healthy Subjects - Outpatient

Primary Investigator: Hendley J. Owen

Otitis Media Study

IRB-HSR#: 13978

Category: Healthy Subjects - Outpatient

Primary Investigator: Birgit Winther, M.D.

Cancer

A Phase I Study of Carboplatin/Paclitaxel/CTEP-supplied agent bevacizumab and CTEP-suppolied agent ABT-888 in newly diagnosed patients with previously untreated epithelial ovarian, fallopian tube or primary peritoneal cancer

IRB-HSR#: 14864

Category: Obstetrics/Gynecology, Cancer (Oncology)

Primary Investigator: Linda Duska, MD

Pilot Study of Dual Modality Surgical Guidance for Non-Palpable Breast Lesions

IRB-HSR#: 11480

Category: Cancer (Oncology)

Primary Investigator: Mark B. Williams, PhD

A Feasibility Study to Evaluate the Safety and Initial Effectiveness of ExAblate MR Guided Focused Ultrasound Surgery in the Treatment of Pain Resulting from Metastatic Bone Tumors with the ExAblate 2100 Conformal Bone System (BM-010)

IRB-HSR#: 14884

Category: Cancer (Oncology)

Primary Investigator: Paul Read, MD

A Multi-Center, Randomized, Placebo-Controlled Phase II Study of Regorafenib in Combination With FOLFIRI (Irinotecan, 5-Fluorouracil, and Leucovorin) Versus Placebo With FOLFIRI as Second-Line Therapy in Patients with K-RAS or BRAF Mutant Metastatic Color

IRB-HSR#: 15688

Category: Cancer (Oncology)

Primary Investigator: Hanna Sanoff, MD

A Multicenter, Open-Label, Phase 2 Study to Evaluate the Safety and Efficacy of NKTR-102 (PEG-Irinotecan) When Given on a Q14 Day or a Q21 Day Schedule in Patients with Metastatic or Unresectable Locally Advanced Platinum-Resistant Ovarian Cancer

IRB-HSR#: 14130

Category: Cancer (Oncology), Obstetrics/Gynecology

Primary Investigator: Linda Duska, M.D.

A Phase 2, Multicenter, Single-Arm, Open-Label Study to Determine the Efficacy and Safety of Single-Agent Lenalidomide (Revlimid)in Patients with Mantle Cell NHL Who Have Relapsed or Progressed After Treatment with Bortezomib or are Refractory to Bortezomib The "EMERGE" Trial

IRB-HSR#: 14183

Category: Cancer (Oncology)

Primary Investigator: Michael E. Williams, MD

A Phase II Neo-Adjuvant Study of Cisplatin, Paclitaxel with or without RAD001 in Patients with Triple-negative Locally Advanced Breast Cancer

IRB-HSR#: 15745

Category: Cancer (Oncology), Women's Health

Primary Investigator: Patrick Dillon, MD

A Phase II Pilot Single Arm Prospective Clinical Trial of Rapid Institution of Helical TomoTherapy-based Radiation Therapy for Patients with Painful Osseous Metastatic Disease

IRB-HSR#: 15625

Category: Cancer (Oncology)

Primary Investigator: Paul Read, MD

A Phase III Clinical Trial Comparing Trastuzumab Given Concurrently with Radiation Therapy and Radiation Therapy Alone for Women with HER2-Positive Ductal Carcinoma in Situ Resected by Lumpectomy (NSABP B-43)

IRB-HSR#: 14464

Category: Cancer (Oncology)

Primary Investigator: Monica Morris, MD

A Phase III Randomized Trial of Lobectomy versus Sublobar Resection

IRB-HSR#: 13622

Category: Cancer (Oncology), Surgery

Primary Investigator: Benjamin Kozower, M.D.

A Phase III Study of Postoperative Radiation Therapy (IMRT)+/- Cetuximab for Locally-Advanced Resected Head and Neck Cancer

IRB-HSR#: 14890

Category: Cancer (Oncology)

Primary Investigator: Paul Read, MD

A Phase III Trial of Irinotecan/5-FU/Leucovorin or Oxaliplatin/5-FU/Leucovorin with Bevacizumab, or Cetuximab (C225), or with the Combination of Bevacizumab and Cetuximab for Patients with Untreated Metastic Adenocarcinoma or the Colon or Rectum

IRB-HSR#: 14308

Category: Cancer (Oncology), Hematology

Primary Investigator: Hanna Sanoff, MD

A Phase III, Randomized Clinical Trial of Standard Adjuvant Endocrine Therapy +/- Chemotherapy in Patients with 1-3 Positive Nodes, Hormone Receptor-Positive and HER2-Negative Breast Cancer with Recurrence Score (RS) of 25 or Less

IRB-HSR#: 15674

Category: Cancer (Oncology)

Primary Investigator: Patrick Dillon, MD

A Randomized Open-Label Multi-Institution Phase II Study of the Combination of Bevacizumab and Erlotinib Compared to Sorafenib in the First-Line Treatment of Patients with Advanced Hepatocellular Carcinoma (HCC)

IRB-HSR#: 15590

Category: Cancer (Oncology)

Primary Investigator: Hanna Sanoff, MD

A Randomized Phase III trial of Maintenance Chemotherapy Comparing 12, Monthly Cycles of Single Agent Paclitaxel or Xyotax (CT-2103) (IND #70177) Versus No Treatment Until Documented Relapse in Women With Advanced Ovarian or Primary Peritoneal Cancer Who Achieve A Complete Clinical Response to Primary Platinum/Taxane Chemotherapy.

IRB-HSR#: 12615

Category: Obstetrics/Gynecology

Primary Investigator: Susan Modesitt, M.D.

A randomized, double-blind, placebo-controlled, multi-center phase III study of RAD001 therapy in poor risk patients with Diffuse Large B-Cell Lymphoma (DLBCL) of RAD001 versus matching placebo after patients have achieved complete response with first-lin

IRB-HSR#: 14648

Category: Cancer (Oncology), Lymphonas

Primary Investigator: Michael E. Williams, MD

ASSURE: Adjuvant Sorafenib or Sunitinib for Unfavorable Renal Carcinoma

IRB-HSR#: 13763

Category: Cancer (Oncology)

Primary Investigator: Christopher Thomas, M.D.

Adults with Cutaneous or Subcutaneous Metastatic Melanoma (Stage IIIB-IV) wanted for research study

IRB-HSR#: 14215

Category: Cancer (Oncology)

Primary Investigator: Craig L. Slingluff, M.D.

Combination Therapy of Topical Imiquimod plus Multipeptide Vaccination for Cutaneous Metastases of Melanoma (Mel53)

IRB-HSR#: 15168

Category: Cancer (Oncology), Melanoma

Primary Investigator: Craig L. Slingluff Jr., MD

Early Stage Lung Cancer Patients wanted for research study.

IRB-HSR#: 14447

Category: Cancer (Oncology), Surgery

Primary Investigator: David R. Jones, M.D.

Effects of a Combined Regime of Flaxseed Oil, Caffeine, Fasting, and Exercise in Women with Recurrent or Multi-drug Resistant Stage III or IV Ovarian Cancer: A Preliminary Study

IRB-HSR#: 14874

Category: Cancer (Oncology), Women's Health

Primary Investigator: Ann Gill Taylor, EdD, RN

European Ewing Tumor Working Initiative of National Groups

IRB-HSR#: 14730

Category: Cancer (Oncology)

Primary Investigator: Kimberly P. Dunsmore, MD

Frailty: An Outcome Predictor for Elderly Gynecologic Oncology Patients?

IRB-HSR#: 15391

Category: Cancer (Oncology), Obsetrics & Gynecology

Primary Investigator: Madeleine Courtney-Brooks, MD

Phase I/II Study of Vorinostat (Suberoylanilide Hydroxamic Acid [SAHA]), Temozolomide, and Radiation Therapy in Patients with Newly Diagnosed Glioblastoma

IRB-HSR#: 15561

Category: Cancer (Oncology)

Primary Investigator: David Schiff, MD

Phase I/II Study of ZD6474 (ZactimaTM) with Radiation Therapy and Concomitant and Adjuvant Temozolomide in Patients with Newly-Diagnosed Glioblastoma

IRB-HSR#: 13291

Category: Cancer (Oncology)

Primary Investigator: David Schiff, M.D.

Phase II Double Blind Randomized Trial Evaluating The Biologic Effect of Levonorgestrel on the Ovarian Epithelium in Women at High Risk for Ovarian Cancer

IRB-HSR#: 13755

Category: Cancer (Oncology)

Primary Investigator: Susan C. Modesitt, M.D.

Phase II trial of accelerated fraction radiotherapy with concomitant capecitabine as neoadjuvant therapy of resectable and borderline resectable pancreas cancer

IRB-HSR#: 15050

Category: Cancer (Oncology)

Primary Investigator: Hanna Sanoff, MD

Phase III Study of Radiation Therapy with or without Temozolomide for Symptomatic or Progressive Low-Grade Gliomas

IRB-HSR#: 14665

Category: Neurology, Cancer

Primary Investigator: David Schiff, M.D.

Randomized Phase III Trial Comparing the Frequency of Major Erythroid Response (MER) to Treatment with Lenalidomide (Revlimid®) Alone and in Combination with Epoetin Alfa (Procrit®) in Subjects with Low-or Intermediate-1 Risk MDS and Symptomatic Anemia

IRB-HSR#: 14434

Category: Cancer (Oncology), Hematology

Primary Investigator: Michael E. Williams, M.D.

Recurrent or Persistent Cervical Cancer

IRB-HSR#: 14351

Category: Cancer (Oncology)

Primary Investigator: Susan Modesitt, M.D.

Seeking Adults 18 and Older with Advanced Indolent Non-Hodgkins Lymphoma or Mantle Cell Lymphoma Who Have Never Received Treatment for Lymphoma

IRB-HSR#: 14518

Category: Cancer (Oncology)

Primary Investigator: John Densmore, M.D.

Standard-dose versus High-dose Radiotherapy for Treatment of Non-Small Cell Lung Cancer

IRB-HSR#: 13516

Category: Cancer (Oncology)

Primary Investigator: James Larner, M.D.

T Cell Activation and Immune Cell Function in Melanoma Patients Treated with recMAGE-A3 and AS15 Immunological Adjuvant System (Mel55)

IRB-HSR#: 15398

Category: Cancer (Oncology), Melanoma

Primary Investigator: Craig L. Slingluff Jr., MD

Vincristine, Dactinomycin, and Lower Doses of Cyclophosphamide With or Without Radiation Therapy for Patients with Newly Diagnosed Low-Risk Embryonal/Botryoid/Spindle Cell Rhabdomyosarcoma

IRB-HSR#: 12680

Category: Cancer (Oncology)

Primary Investigator: Kimberly P. Dunsmore, MD

Women Ages 18 and Above with Platinum Sensitive, Recurrent Ovarian, Fallopian Tube, or Primary Peritoneal Cancer Needed for Research Study

IRB-HSR#: 13501

Category: Obstetrics/Gynecology

Primary Investigator: Susan Modesitt, M.D.

Cancer (Children)

A Phase III Randomized Trial of Gemtuzumab Ozogamicin (Mylotarg(r) Combined with Conventional Chemotherapy for De Novo Acute Myeloid Leukemia (AML) in Children, Adolescents, and Young Adults

IRB-HSR#: 13315

Category: Cancer (Oncology), Pediatrics

Primary Investigator: Kimberly Dunsmore, M.D.

A Randomized Trial of the European and American Osteosarcoma Study Group to Optimize Treatment Strategies for Resectable Osteosarcoma Based on Histological Response to Pre-operative Chemotherapy: A Phase III Intergroup Study

IRB-HSR#: 12547

Category: Cancer (Oncology), Pediatrics

Primary Investigator: Kimberly Dunsmore, M.D.

Children aged 1-10 with ALL Sought for Research Study

IRB-HSR#: 12087

Category: Cancer (Oncology), Pediatrics

Primary Investigator: Kimberly Dunsmore, M.D.

Children over 10 years of age with ALL Leukemia sought for research study

IRB-HSR#: 11847

Category: Cancer (Oncology), Pediatrics

Primary Investigator: Kimberly Dunsmore, M.D.

Clinical Trial for Children and Adolescents with Intermediate-risk Neuroblastoma

IRB-HSR#: 13633

Category: Cancer (Oncology), Pediatrics

Primary Investigator: Kimberly Dunsmore, M.D.

Clinical Trial for Patient with Acute Lymphoblastic Leukemia

IRB-HSR#: 14391

Category: Cancer (Oncology), Pediatrics

Primary Investigator: Kimberly Dunsmore, M.D.

Clinical Trials for Patients With Intermediate-risk, Newly Diagnosed Rhabdomyosarcoma

IRB-HSR#: 13667

Category: Cancer (Oncology), Pediatrics

Primary Investigator: Kimberly Dunsmore, M.D.

European Ewing Tumor Working Initiative of National Groups

IRB-HSR#: 14730

Category: Cancer (Oncology)

Primary Investigator: Kimberly P. Dunsmore, MD

Phase III Randomized Study of Chimeric Antibody 14.18 (Ch14.18) in High Risk Neuroblastoma Following Myeloablative Therapy and Autologous Stem Cell Rescue

IRB-HSR#: 14593

Category: Cancer (Oncology), Pediatrics

Primary Investigator: Kimberly Dunsmore, M.D.

Risk-Based Treatment for Non-Rhabdomyosarcoma Soft Tissue Sarcomas (NRSTS) in Patients Under 30 Years of Age COG#: ARST0332

IRB-HSR#: 14624

Category: Cancer (Oncology), Pediatrics

Primary Investigator: Kimberly Dunsmore, M.D.

Treatment for Very Low, Low and Standard Risk Favorable Histology Wilms Tumor

IRB-HSR#: 13671

Category: Cancer (Oncology)

Primary Investigator: Kimberly Dunsmore, M.D.

Treatment of Newly Diagnosed Higher Risk Favorable Histology Wilms Tumors

IRB-HSR#: 14379

Category: Cancer (Oncology), Pediatrics

Primary Investigator: Kimberly Dunsmore, M.D.

UVa Health System, Department of Pediatrics seeks: children, adolescents, women and men with hepatoblastoma for research study. The patient must be less than 22 years old at the time of diagnosis.

IRB-HSR#: 14764

Category: Cancer (Oncology), Pediatrics

Primary Investigator: Kimberly P. Dunsmore

Vincristine, Dactinomycin, and Lower Doses of Cyclophosphamide With or Without Radiation Therapy for Patients with Newly Diagnosed Low-Risk Embryonal/Botryoid/Spindle Cell Rhabdomyosarcoma

IRB-HSR#: 12680

Category: Cancer (Oncology)

Primary Investigator: Kimberly P. Dunsmore, MD

Continuum Home Health

No clinical trials available at this time.

Dentistry

No clinical trials available at this time.

Dentistry (Children)

No clinical trials available at this time.

Dermatology

T Cells in Allergic Disease

IRB-HSR#: 13166

Category: Dermatology/Plastic Surgery

Primary Investigator: Judith Woodfolk

Developmental and Behavioral (Children)

Asthma and Breathlessness in School Age Children

IRB-HSR#: 12280

Category: Musculoskeletal/Sports Medicine

Primary Investigator: Thomas A Platts-Mills

Diabetes and Endocrinology (Children)

Adolescent Hormone Study

IRB-HSR#: 10504

Category: Healthy Subjects - Inpatient

Primary Investigator: Christopher McCartney, M.D.

Effect of Metformin on Sensitivity of the GnRH Pulse Generator to Suppression by Estradiol and Progesterone in Hyperandrogenic Adolescent Girls (JCM025)

IRB-HSR#: 13789

Category: Endocrinology, Obesity

Primary Investigator: John C Marshall, MD

Evaluation of Adrenal Androgen Production in Normal and Obese Girls After Suppression and Stimulation (JCM022)

IRB-HSR#: 12702

Category: Endocrinology, Healthy Subjects - Inpatient

Primary Investigator: John Marshall, M.D.

Reproductive Hormone Study

IRB-HSR#: 13552

Category: Healthy Subjects - Inpatient

Primary Investigator: Christopher McCartney, M.D.

Reproductive Hormone Study

IRB-HSR#: 13950

Category: Healthy Subjects - Inpatient

Primary Investigator: Christopher McCartney, M.D.

S-Nitrosylation & Inflammation in Obstructive Sleep Apnea

IRB-HSR#: 13441

Category: Endocrinology

Primary Investigator: Mark DeBoer

Time Course of Waking vs. Sleep-Associated LH Pulse Frequency Suppression in Response to Progesterone in Late Pubertal Girls with and Without Hyperandrogenemia (CRM003)

IRB-HSR#: 13717

Category: Healthy Subjects - Inpatient, Pediatrics

Primary Investigator: Christopher McCartney, M.D.

Diabetes & Metabolism

Determination of the Role of Dihydrotestosterone in Mediating Relative GnRH Pulse Generator Resistance to Ovarian Steroid Feedback in Adults with PCOS (JCM018)

IRB-HSR#: 10842

Category: Endocrinology, Healthy Subjects - Inpatient

Primary Investigator: Christopher McCartney M.D.

Determine the Temporal Relationships Between Pulsatile Acyl- and Des-Acyl Ghrelin Secretion and Plasma Concentrations of Insulin, Cortisol, and Growth Hormone in Healthy Lean Insulin-Sensitive and Obese Insulin-Resistant Adults (MOT105)

IRB-HSR#: 13376

Category: Endocrinology, Healthy Subject Studies, Healthy Subjects - Inpatient

Primary Investigator: Michael O. Thorner, M.D.

Effect of age on insulin mediated regulation of ghrelin

IRB-HSR#: 12223

Category: Healthy Subject Studies

Primary Investigator: Nass Ralf, M.D.

Healthy Women Wanted for Breast-Feeding Study

IRB-HSR#: 12441

Category: Healthy Subjects - Outpatient

Primary Investigator: Sue Brown, M.D.

Influence of Hyperandrogenemia on the Sleep-Associated Slowing of Follicular LH Frequency in Adult Polycystic Ovary Syndrome (CRM004)

IRB-HSR#: 14067

Category: Endocrinology, Healthy Subjects - Inpatient

Primary Investigator: Christopher McCartney M.D.

Insulin mediated forearm muscle microvascular recruitment and insulin uptake in healthy subjects (EJB039)

IRB-HSR#: 12127

Category: Healthy Subject Studies

Primary Investigator: Eugene Barrett, M.D., Ph.D.

PYR-210: A Randomized, Double-Blind, Placebo-Controlled, Multi-Center, Phase 2b Study to Evaluate the Safety and Efficacy of Pyridorin (Pyridoxamine Dihydrochloride) in Patients with Nephropathy Due to Type 2 Diabetes

IRB-HSR#: 13884

Category: Endocrinology, Nephrology (Kidney)

Primary Investigator: Bolton W. Kline, M.D.

Pharmacogenetics of Metformin Action in PCOS (WSE035)

IRB-HSR#: 14041

Category: Endocrinology, Women's Health

Primary Investigator: William S. Evans, M.D.

Promoting "Stories of Success": Enhancing Diabetes Self-Care (SWU001)

IRB-HSR#: 14478

Category: Healthy Subject Studies

Primary Investigator: Sharon Utz, Ph.D., R.N.

Reproductive Hormone Studies

IRB-HSR#: 13368

Category: Women's Health, Healthy Subjects - Inpatient

Primary Investigator: Christopher McCartney M.D.

S-Nitrosylation & Inflammation in Obstructive Sleep Apnea

IRB-HSR#: 13441

Category: Endocrinology

Primary Investigator: Mark DeBoer

The impact of glucose (peripheral or luminal) and/or insulin on the short-term regulation of ghrelin

IRB-HSR#: 12561

Category: Healthy Subject Studies

Primary Investigator: Ralf Nass M.D., P.I.

The impact of insulin on the short term regulation of ghrelin.(RMN003)

IRB-HSR#: 13109

Category: Healthy Subject Studies | Healthy Subjects - Outpatient

Primary Investigator: Ralf Nass MD, PI

UVA Islet Cell Transplantion in Patients with Type I Diabetes (KBL004)

IRB-HSR#: 12839

Category: Endocrinology, Nephrology (Kidney)

Primary Investigator: Kenneth Brayman, M.D., Ph.D.

Urinary Angiotensinogen Excretion in Normal Subjects and Patients with Type II Diabetes Mellitus (RMC032)

IRB-HSR#: 12940

Category: Endocrinology , Nephrology (Kidney)

Primary Investigator: Robert M. Carey, M.D.

Digestive (Children)

No clinical trials available at this time.

Digestive Health

A Phase 3, Randomized, Placebo-Controlled, Blinded, Multicenter Study of the Induction and Maintenance of Clinical Response and Remission by Vedolizumab (MLN0002) in Patients with Moderate to Severe Ulcerative Colitis

IRB-HSR#: 14493

Category: Gastroenterology/Hepatology

Primary Investigator: Behm Brian, M.D.

Effect of Metformin on Sensitivity of the GnRH Pulse Generator to Suppression by Estradiol and Progesterone in Hyperandrogenic Adolescent Girls (JCM025)

IRB-HSR#: 13789

Category: Endocrinology, Obesity

Primary Investigator: John C Marshall, MD

Pravastatin Therapy in Patients with Active Crohn's Disease: A Pilot Study

IRB-HSR#: 11453

Category: Gastroenterology/Hepatology

Primary Investigator: Behm Brian, M.D.

Eye Care

No clinical trials available at this time.

Eye Care (Children)

No clinical trials available at this time.

General Pediatrics (Children)

No clinical trials available at this time.

Genetics (Children)

No clinical trials available at this time.

Head and Neck (Children)

Effectiveness of Surface Cleaners in Reducing Transfer of Human Rhinovirus (HRV) to Fingertips through Activities of Daily Life (ADL)

IRB-HSR#: 13829

Category: Otolaryngology

Primary Investigator: Birgit Winther, M.D.

Ear, Nose and Throat

Effectiveness of Surface Cleaners in Reducing Transfer of Human Rhinovirus (HRV) to Fingertips through Activities of Daily Life (ADL)

IRB-HSR#: 13829

Category: Otolaryngology

Primary Investigator: Birgit Winther, M.D.

Otitis Media Study

IRB-HSR#: 13978

Category: Healthy Subjects - Outpatient

Primary Investigator: Birgit Winther, M.D.

Heart

Acute Venous Thrombosis: Thrombus Removal With Adjunctive Catheter-Directed Thrombolysis (The ATTRACT Trial)

IRB-HSR#: 14442

Category: Cardiology/Vascular

Primary Investigator: John F. Angle, MD

Evaluation of the GORE TAG® Thoracic Endoprosthesis 45 mm for the Primary Treatment of Aneurysms of the Descending Thoracic Aorta (Protocol Number: TAG 06-02)

IRB-HSR#: 12894

Category: Cardiology/Vascular , Surgery

Primary Investigator: Alan Matsumoto, M.D.

ReCardioversion in Afib Study

IRB-HSR#: 13790

Category: Heart Center

Primary Investigator: John Ferguson

Heart (Children)

Acute Venous Thrombosis: Thrombus Removal With Adjunctive Catheter-Directed Thrombolysis (The ATTRACT Trial)

IRB-HSR#: 14442

Category: Cardiology/Vascular

Primary Investigator: John F. Angle, MD

Immunology and Rheumatology (Children)

No clinical trials available at this time.

Infectious Disease (Children)

No clinical trials available at this time.

Infectious Diseases

No clinical trials available at this time.

Kidney

IRB-HSR#: 13884

Category: Endocrinology, Nephrology (Kidney)

Primary Investigator: Bolton W. Kline, M.D.

UVA Islet Cell Transplantion in Patients with Type I Diabetes (KBL004)

IRB-HSR#: 12839

Category: Endocrinology, Nephrology (Kidney)

Primary Investigator: Kenneth Brayman, M.D., Ph.D.

Urinary Angiotensinogen Excretion in Normal Subjects and Patients with Type II Diabetes Mellitus (RMC032)

IRB-HSR#: 12940

Category: Endocrinology , Nephrology (Kidney)

Primary Investigator: Robert M. Carey, M.D.

Kidney Care (Children)

No clinical trials available at this time.

Neonatology (Children)

No clinical trials available at this time.

Neurology and Neurosurgery (Children)

No clinical trials available at this time.

Neurosciences

A Historical-controlled, Multicenter, Double-blind, Randomized Trial to Assess the Efficacy and Safety of Conversion to Lacosamide 400mg/day Monotherapy in Subjects with Partial-onset Seizures.

IRB-HSR#: 13381

Category: Neurology

Primary Investigator: Nathan B. Fountain

Are you a family member of someone with memory loss?

IRB-HSR#: 14290

Category: Neurosciences

Primary Investigator: Karen Rose

CONCERT: A Phase 3 Multicenter, Randomized, Placebo-Controlled, Double-Blind Twelve-Month Safety and Efficacy Study Evaluating Dimebon in Patients with Mild-To-Moderate Alzheimer's Disease on Donepezil

IRB-HSR#: 14280

Category: Neurosciences

Primary Investigator: David S Geldmacher, M.D.

Cognitive Stability Index Validation Study

IRB-HSR#: 14221

Category: Neurology

Primary Investigator: Donna K. Broshek

Cooperative Huntington's Disease Observational Research Trial (COHORT)

IRB-HSR#: 12184

Category: Neurosciences

Primary Investigator: M. B. Harrison, M.D.

Focused Ultrasound Surgery Trial

IRB-HSR#: 16034

Category: Neurology

Primary Investigator: Jeff Elias, MD

GORE HELEX Septal Occluder and Antiplatelet Medical Management for Reduction of Recurrent Stroke or Imaging-Confirmed TIA in Patients with Patent Foramen Ovale (PFO)- The GORE REDUCE Study

IRB-HSR#: 14012

Category: Neurology

Primary Investigator: Nina Solenski

Genetic Risk Factors for Medication-Related Hemorrhagic Stroke

IRB-HSR#: 11535

Category: Neurology

Primary Investigator: Bradford Worrall, M.D.

Impulse Control Disorders and Parkinson's Disease: the Effect of Dopamine Therapy on Decision-Making and Response Inhibition

IRB-HSR#: 14451

Category: Neurology

Primary Investigator: Daniel O. Claassen, M.D.

Insulin Resistance Intervention after Stroke (IRIS) Trial

IRB-HSR#: 11520

Category: Neurology

Primary Investigator: Karen C. Johnston, M.D., M.S.c.

Neural correlates of pretense

IRB-HSR#: 14432

Category: Neurology

Primary Investigator: James P. Morris

Novel Pharmacotherapy for Dual Dependence

IRB-HSR#: 11620

Category: Healthy Subjects - Inpatient

Primary Investigator: Johnson Bankole, M.D.

Phase III Study of Radiation Therapy with or without Temozolomide for Symptomatic or Progressive Low-Grade Gliomas

IRB-HSR#: 14665

Category: Neurology, Cancer

Primary Investigator: David Schiff, M.D.

Primary Progressive Multiple Sclerosis research study.

IRB-HSR#: 14115

Category: Neurology

Primary Investigator: Myla Goldman, M.D.

Reducing Alcohol Exposed Pregnancy Risk

IRB-HSR#: 14460

Category: Psychiatry/Psychology, Women's Health, Healthy Subjects - Outpatient

Primary Investigator: Karen Ingersoll, Ph.D.

Research Opportunity for Adults

IRB-HSR#: 14951

Category: Neurology

Primary Investigator: DeKosky, Steven T.

Subcortical contributions to imitation

IRB-HSR#: 14510

Category: Neurology

Primary Investigator: James P. Morris

The Effect of Parkinson's Disease on Event-Related Brain Potentials Linked to Response Selection and Inhibition

IRB-HSR#: 14141

Category: Healthy Subject Studies

Primary Investigator: Scott Wylie, Ph.D.

UVA Health System and the Social Neuroscience Lab in the Psychology Department seeks MEN Ages 18 - 45 for Research Study

IRB-HSR#: 14570

Category: Psychiatry/Psychology

Primary Investigator: James Morris, Ph.D.

Nutrition (Children)

No clinical trials available at this time.

Orthopaedics

Adolescents Ages 10-15 with Idiopathic Scoliosis for a Research Study

IRB-HSR#: 12688

Category: Musculoskeletal/Sports Medicine

Primary Investigator: Mark F. Abel

Adults with Low Back Pain for Exercise Study

IRB-HSR#: 14046

Category: Musculoskeletal/Sports Medicine

Primary Investigator: Susan A. Saliba, Ph.D., ATC, PT

Children and Adolescents Ages 8 Years and up for a Research Study

IRB-HSR#: 12955

Category: Musculoskeletal/Sports Medicine

Primary Investigator: Bradford C Bennett

Do You Have an Ankle Sprain?

IRB-HSR#: 13960

Category: Healthy Subject Studies

Primary Investigator: Jay Hertel, Ph.D., A.T.C., FNATA

Men and Women Ages 16-65 who Have Had an Injury or Reconstruction to the Anterior Cruciate Ligament Needed for a Research Study

IRB-HSR#: 13691

Category: Musculoskeletal/Sports Medicine

Primary Investigator: Joseph Hart, Ph.D, ATC

Men and Women ages 18 to 55 who have Recently Torn a Knee Ligament and have Thigh Muscle Weakness needed for a Research Study

IRB-HSR#: 13398

Category: Musculoskeletal/Sports Medicine

Primary Investigator: Joseph Hart, Ph.D, ATC

Modeling and Simulation of the Vertical Climber

IRB-HSR#: 14287

Category: Musculoskeletal/Sports Medicine

Primary Investigator: Silvia Blemker,

Patients with Lumbar Spinal Stenosis Needed for Research Study

IRB-HSR#: 13852

Category: Musculoskeletal/Sports Medicine

Primary Investigator: Robert P. Wilder, M.D.

Seeking Adults 18-40 with a History of Knee Injury and/or Surgery for a Research Study

IRB-HSR#: 13648

Category: Musculoskeletal/Sports Medicine

Primary Investigator: Christopher D. Ingersoll

Spectrum of Disability with Chronic Ankle Instability

IRB-HSR#: 14010

Category: Healthy Subject Studies

Primary Investigator: Jay Hertel, Ph.D., A.T.C., FNATA

The Relationship Between Trunk Neuromuscular Control and Running Mechanics Following Cycling in Triathletes

IRB-HSR#: 14723

Category: Musculoskeletal/Sports Medicine

Primary Investigator: Joseph Hart, Ph.D., ATC

Orthopaedics (Children)

Accrual of Bone Mineral in Children with Cerebral Palsy

IRB-HSR#: 13503

Category: Pediatrics

Primary Investigator: Christine M. Houlihan

Adolescents Ages 10-15 with Idiopathic Scoliosis for a Research Study

IRB-HSR#: 12688

Category: Musculoskeletal/Sports Medicine

Primary Investigator: Mark F. Abel

Children and Adolescents Ages 8 Years and up for a Research Study

IRB-HSR#: 12955

Category: Musculoskeletal/Sports Medicine

Primary Investigator: Bradford C Bennett

Do You Have an Ankle Sprain?

IRB-HSR#: 13960

Category: Healthy Subject Studies

Primary Investigator: Jay Hertel, Ph.D., A.T.C., FNATA

Pain Management

No clinical trials available at this time.

Palliative Care

No clinical trials available at this time.

Pituitary

Influence of Hyperandrogenemia on the Sleep-Associated Slowing of Follicular LH Frequency in Adult Polycystic Ovary Syndrome (CRM004)

IRB-HSR#: 14067

Category: Endocrinology, Healthy Subjects - Inpatient

Primary Investigator: Christopher McCartney M.D.

Plastic Surgery

A Prospective, Two-center, Randomized, Crossover Clinical Investigation of Marathon® and Cavilon to Treat Peri-Wound Maceration in Subjects with Venous Leg Ulcers

IRB-HSR#: 14671

Category: Healthy Subject Studies

Primary Investigator: George T. Rodeheaver

Dust Mite, Cockroach & Cat Allergens in Houses/Asthma

IRB-HSR#: 2383

Category: Dermatology/Plastic Surgery

Primary Investigator: Thomas A Platts-Mills,

T Cells in Allergic Disease

IRB-HSR#: 13166

Category: Dermatology/Plastic Surgery

Primary Investigator: Judith Woodfolk

Plastic Surgery (Children)

No clinical trials available at this time.

Primary Care

No clinical trials available at this time.

Psychiatry

A Gene by Pharmacotherapy Interaction on Alcohol-elicited Craving and Sensitivity to the Acute Effects of Alcohol.

IRB-HSR#: 13464

Category: Psychiatry/Psychology

Primary Investigator: Heather M. Haughey, Ph.D.

A PHASE 2, DOUBLE-BLIND, PLACEBO CONTROLLED TRIAL TO ASSESS THE EFFICACY OF LEVETIRACETAM EXTENDED RELEASE IN VERY HEAVY DRINKERS

IRB-HSR#: 14453

Category: Psychiatry/Psychology

Primary Investigator: Bankole Johnson, M.D.

A Phase III, Randomized, Double-Blind, Placebo-Controlled, Multi-Center Study of the Safety and Efficacy of Libigel® for the Treatment of Hypoactive Sexual Desire Disorder in Surgically Menopausal Women

IRB-HSR#: 13134

Category: Obstetrics/Gynecology, Psychiatry/Psychology, Women's Health

Primary Investigator: Anita H. Clayton, M.D.

Are you 50 or older and suffering from lack of sexual desire?

IRB-HSR#: 13557

Category: Psychiatry/Psychology

Primary Investigator: Anita H. Clayton

Combined Pharmacotherapies for Alcoholism/Genetic Variations and Treatment Response Among Alcoholics

IRB-HSR#: 12790

Category: Psychiatry/Psychology

Primary Investigator: Bankole Johnson, M.D.

Combining Medications for the Treatment of Alcohol Dependence: An Inpatient Preliminary Study (BAJ003)

IRB-HSR#: 13521

Category: Psychiatry/Psychology

Primary Investigator: Bankole Johnson, M.D.

Dose Response of Mirtazapine to Methamphetamine Induced Interest, Mood Elevation, and Reward

IRB-HSR#: 13222

Category: Pharmacology/Toxicology

Primary Investigator: Marzani-Nissen Gabrielle,

Healthy Gay and Lesbian Couples are Needed for a Research Study

IRB-HSR#: 12984

Category: Psychiatry/Psychology

Primary Investigator: James A. Coan, M.D.

Lab Trials to Develop Medications for Cocaine Dependence--Study 1(BAJ002)

IRB-HSR#: 12350

Category: Psychiatry/Psychology

Primary Investigator: Bankole Johnson, M.D.

Medication Development for Cocaine Dependence

IRB-HSR#: 11578

Category: Psychiatry/Psychology

Primary Investigator: Bankole Johnson, M.D.

Medications Development for the Treatment of Cannabis Related Disorders (HMH001)

IRB-HSR#: 14392

Category: Psychiatry/Psychology

Primary Investigator: Heather M. Haughey

Novel Pharmacotherapy for Dual Dependence

IRB-HSR#: 11620

Category: Healthy Subjects - Inpatient

Primary Investigator: Johnson Bankole, M.D.

Ondansetron for the Treatment of Heavy Drinking among Emerging Adults

IRB-HSR#: 13610

Category: Psychiatry/Psychology

Primary Investigator: Bankole Johnson, M.D.

Reducing Alcohol Exposed Pregnancy Risk

IRB-HSR#: 14460

Category: Psychiatry/Psychology, Women's Health, Healthy Subjects - Outpatient

Primary Investigator: Karen Ingersoll, Ph.D.

Supplementation of Antidepressants with Fatty Acid Therapy (Sad Fat)

IRB-HSR#: 14503

Category: Psychiatry/Psychology

Primary Investigator: Anita H. Clayton

UVA Health System and the Social Neuroscience Lab in the Psychology Department seeks MEN Ages 18 - 45 for Research Study

IRB-HSR#: 14570

Category: Psychiatry/Psychology

Primary Investigator: James Morris, Ph.D.

UVA Researchers Seek Voluteers for Womens Health Study

IRB-HSR#: 12794

Category: Psychiatry/Psychology

Primary Investigator: Karen Ingersoll, Ph.D.

Young Adult Driving Study

IRB-HSR#: 14500

Category: Healthy Subjects - Outpatient

Primary Investigator: Richard L. Merkel, M.D.

Psychiatry (Children)

No clinical trials available at this time.

Pulmonary & Respiratory Care

A Prospective, Randmomized, Controlled Multi-center Clinical Trial to Evaluate the Safety and Effeciveness of the IBV Valve System for the Treatment of Severe Emphysema (JDT003)

IRB-HSR#: 12648

Category: Pulmonary/Respiratory

Primary Investigator: Jonathon D. Truwit

ARTEMIS: A Phase 3, Randomized, Double Blind, Placebo Controlled, Multi Center, Parallel Group, Event Driven Study to Evaluate the Efficacy and Safety of Ambrisentan in Subjects with Early Idiopathic Pulmonary Fibrosis (IPF)

IRB-HSR#: 14169

Category: Pulmonary/Respiratory

Primary Investigator: George Verghese, M.D.

CNS Effects of Inhaled Xenon

IRB-HSR#: 14396

Category: Pulmonary/Respiratory

Primary Investigator: Talissa Altes, M.D.

Common Cold

IRB-HSR#: 12656

Category: Immunology/Infectious Diseases, Pulmonary/Respiratory, Healthy Subjects - Outpatient

Primary Investigator: Peter W. Heymann

Hyperpolarized Helium-3 MR Lung Imaging Findings in Asthmatics

IRB-HSR#: 8559

Category: Pulmonary/Respiratory

Primary Investigator: Eduard E. de Lange

Hyperpolarized Xenon-129 MR imaging of the Lung

IRB-HSR#: 13740

Category: Pulmonary/Respiratory

Primary Investigator: Talissa Altes, M.D.

Mechanisms and Treatment of Sleep-Disordered Breathing in Chronic Obstructive Pulmonary Disease (CDB001)

IRB-HSR#: 13855

Category: Pulmonary/Respiratory

Primary Investigator: Cynthia D. Brown, M.D.

People With Obstructive Sleep-Disordered Breathing (SDB) Generate High-Frequency Sounds When Inspiratory Effort is High as Measured by Esophageal Pressure

IRB-HSR#: 11486

Category: Pulmonary/Respiratory

Primary Investigator: Christopher M. Rembold, M.D.

Standard-dose versus High-dose Radiotherapy for Treatment of Non-Small Cell Lung Cancer

IRB-HSR#: 13516

Category: Cancer (Oncology)

Primary Investigator: James Larner, M.D.

Study of Asthma and Nasal Steroids (STAN)(WGT003)

IRB-HSR#: 15092

Category: Pulmonary/Respiratory, Pediatrics

Primary Investigator: W Gerald Teague MD

The Study of Soy Isoflavones in Asthma(SOYA)(WGT002)

IRB-HSR#: 15037

Category: Pulmonary/Respiratory, Pediatrics

Primary Investigator: W Gerald Teague MD

Radiology & Medical Imaging

No clinical trials available at this time.

Rehabilitation

The Relationship Between Hepcidin Levels and Menstrual Cycle Phase (SAS003)The Relationship Between Hepcidin Levels and Menstrual Cycle Phase (SAS003)

IRB-HSR#: 13053

Category: Healthy Subject Studies

Primary Investigator: Susan Saliba, Ph.D.

Rehabilitation (Children)

No clinical trials available at this time.

Respiratory and Allergy Care (Children)

Study of Asthma and Nasal Steroids (STAN)(WGT003)

IRB-HSR#: 15092

Category: Pulmonary/Respiratory, Pediatrics

Primary Investigator: W Gerald Teague MD

T Cell Subsets Associated with IgE Antibody Responses in Early Life

IRB-HSR#: 12309

Category: Dermatology/Plastic Surgery

Primary Investigator: Woodfolk Judith, A

The Study of Soy Isoflavones in Asthma(SOYA)(WGT002)

IRB-HSR#: 15037

Category: Pulmonary/Respiratory, Pediatrics

Primary Investigator: W Gerald Teague MD

Speech Language Pathology (Children)

No clinical trials available at this time.

Teen Health (Children)

Adolescent Hormone Study

IRB-HSR#: 10504

Category: Healthy Subjects - Inpatient

Primary Investigator: Christopher McCartney, M.D.

Adolescent Hormone Study

IRB-HSR#: 13502

Category: Healthy Subjects - Inpatient

Primary Investigator: John C Marshall, M.D.

Reproductive Hormone Studies

IRB-HSR#: 13660

Category: Healthy Subjects - Inpatient

Primary Investigator: John C Marshall, M.D.

Reproductive Hormone Study

IRB-HSR#: 13552

Category: Healthy Subjects - Inpatient

Primary Investigator: Christopher McCartney, M.D.

Reproductive Hormone Study

IRB-HSR#: 13950

Category: Healthy Subjects - Inpatient

Primary Investigator: Christopher McCartney, M.D.

Reproductive Hormones Study

IRB-HSR#: 14100

Category: Healthy Subjects - Inpatient

Primary Investigator: John C Marshall, M.D.

Time Course of Waking vs. Sleep-Associated LH Pulse Frequency Suppression in Response to Progesterone in Late Pubertal Girls with and Without Hyperandrogenemia (CRM003)

IRB-HSR#: 13717

Category: Healthy Subjects - Inpatient, Pediatrics

Primary Investigator: Christopher McCartney, M.D.

Transplantation

Adults Undergoing Liver Transplant Wanted for Tissue Donation Study

IRB-HSR#: 11644

Category: Surgery

Primary Investigator: Timothy M. Schmitt

UVA Islet Cell Transplantion in Patients with Type I Diabetes (KBL004)

IRB-HSR#: 12839

Category: Endocrinology, Nephrology (Kidney)

Primary Investigator: Kenneth Brayman, M.D., Ph.D.

Urology

No clinical trials available at this time.

Urology (Children)

No clinical trials available at this time.

Vascular

A Prospective, Two-center, Randomized, Crossover Clinical Investigation of Marathon® and Cavilon to Treat Peri-Wound Maceration in Subjects with Venous Leg Ulcers

IRB-HSR#: 14671

Category: Healthy Subject Studies

Primary Investigator: George T. Rodeheaver

A Safety and Efficacy Trial Evaluating the Use of Apixaban for the Extended Treatment of Deep Vein Thrombosis and Pulmonary Embolism (CV 185057)

IRB-HSR#: 13883

Category: Cardiology/Vascular

Primary Investigator: B. Gail Macik

Acute Venous Thrombosis: Thrombus Removal With Adjunctive Catheter-Directed Thrombolysis (The ATTRACT Trial)

IRB-HSR#: 14442

Category: Cardiology/Vascular

Primary Investigator: John F. Angle, MD

Evaluation of Outcomes Following Mitral Valve Repair/Replacement in Severe Chronic Ischemic Mitral Regurgitation

IRB-HSR#: 13874

Category: Surgery

Primary Investigator: Irving L. Kron, M.D.

Evaluation of the GORE TAG® Thoracic Endoprosthesis 45 mm for the Primary Treatment of Aneurysms of the Descending Thoracic Aorta (Protocol Number: TAG 06-02)

IRB-HSR#: 12894

Category: Cardiology/Vascular , Surgery

Primary Investigator: Alan Matsumoto, M.D.

Women's Health

IRB-HSR#: 14864

Category: Obstetrics/Gynecology, Cancer (Oncology)

Primary Investigator: Linda Duska, MD

IRB-HSR#: 14130

Category: Cancer (Oncology), Obstetrics/Gynecology

Primary Investigator: Linda Duska, M.D.

IRB-HSR#: 13134

Category: Obstetrics/Gynecology, Psychiatry/Psychology, Women's Health

Primary Investigator: Anita H. Clayton, M.D.

A Phase IV Clinical Study to Evaluate the Safety of MR-Guided Focused Ultrasound Treatment of Uterine Fibroids With Enhanced Sonication Techniques

IRB-HSR#: 15182

Category: Women's Health

Primary Investigator: Alan Matsumoto, MD

IRB-HSR#: 12615

Category: Obstetrics/Gynecology

Primary Investigator: Susan Modesitt, M.D.

Adolescent Hormone Study

IRB-HSR#: 10504

Category: Healthy Subjects - Inpatient

Primary Investigator: Christopher McCartney, M.D.

Adolescent Hormone Study

IRB-HSR#: 13502

Category: Healthy Subjects - Inpatient

Primary Investigator: John C Marshall, M.D.

Formula Switching for Infants

IRB-HSR#: 14281

Category: Obstetrics/Gynecology

Primary Investigator: James Sutphen

Genes that Account for Variation in Mammographic Breast Density

IRB-HSR#: 13372

Category: Women's Health

Primary Investigator: Jennifer Harvey, MD

Healthy Women Wanted for Breast-Feeding Study

IRB-HSR#: 12441

Category: Healthy Subjects - Outpatient

Primary Investigator: Sue Brown, M.D.

Novel Systems for Molecular Breast Imaging

IRB-HSR#: 8825

Category: Women's Health

Primary Investigator: Mark B. Williams

Pharmacogenetics of Metformin Action in PCOS (WSE035)

IRB-HSR#: 14041

Category: Endocrinology, Women's Health

Primary Investigator: William S. Evans, M.D.

Phase II Double Blind Randomized Trial Evaluating The Biologic Effect of Levonorgestrel on the Ovarian Epithelium in Women at High Risk for Ovarian Cancer

IRB-HSR#: 13755

Category: Cancer (Oncology)

Primary Investigator: Susan C. Modesitt, M.D.

Reducing Alcohol Exposed Pregnancy Risk

IRB-HSR#: 14460

Category: Psychiatry/Psychology, Women's Health, Healthy Subjects - Outpatient

Primary Investigator: Karen Ingersoll, Ph.D.

Reproductive Hormone Studies

IRB-HSR#: 13368

Category: Women's Health, Healthy Subjects - Inpatient

Primary Investigator: Christopher McCartney M.D.

Reproductive Hormone Studies

IRB-HSR#: 13660

Category: Healthy Subjects - Inpatient

Primary Investigator: John C Marshall, M.D.

Reproductive Hormone Study

IRB-HSR#: 13552

Category: Healthy Subjects - Inpatient

Primary Investigator: Christopher McCartney, M.D.

Reproductive Hormone Study

IRB-HSR#: 13950

Category: Healthy Subjects - Inpatient

Primary Investigator: Christopher McCartney, M.D.

Reproductive Hormones Study

IRB-HSR#: 14100

Category: Healthy Subjects - Inpatient

Primary Investigator: John C Marshall, M.D.

Research Study of Sexually Active Women

IRB-HSR#: 11959

Category: Women's Health

Primary Investigator: Barbara Parker, Ph.D. FAAN

The Effect of Aerobic Exercise Training on Endothelial Function in African American and Caucasian Women (ALW018)

IRB-HSR#: 13252

Category: Healthy Subjects - Outpatient

Primary Investigator: Arthur Weltman, Ph.D.

The Relationship Between Hepcidin Levels and Menstrual Cycle Phase (SAS003)The Relationship Between Hepcidin Levels and Menstrual Cycle Phase (SAS003)

IRB-HSR#: 13053

Category: Healthy Subject Studies

Primary Investigator: Susan Saliba, Ph.D.

Time Course of Waking vs. Sleep-Associated LH Pulse Frequency Suppression in Response to Progesterone in Late Pubertal Girls with and Without Hyperandrogenemia (CRM003)

IRB-HSR#: 13717

Category: Healthy Subjects - Inpatient, Pediatrics

Primary Investigator: Christopher McCartney, M.D.

UVA Researchers Seek Voluteers for Womens Health Study

IRB-HSR#: 12794

Category: Psychiatry/Psychology

Primary Investigator: Karen Ingersoll, Ph.D.

Women Ages 18 and Above with Platinum Sensitive, Recurrent Ovarian, Fallopian Tube, or Primary Peritoneal Cancer Needed for Research Study

IRB-HSR#: 13501

Category: Obstetrics/Gynecology

Primary Investigator: Susan Modesitt, M.D.

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