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Jonathon  D.  Truwit,  MD

Pulmonary and Critical Care Medicine

Contact Information

Address: P.O. Box 800546, Charlottesville, VA, 22908-0546
Phone: 434.243.7088 Fax: 434.982.0402

Training & Certification


Internal Medicine, Vanderbilt University


Pulmonary Medicine, Vanderbilt University

  • Internal Medicine, 1986
  • Pulmonary Medicine, 1988
  • Critical Care Medicine, 1989

Clinical Practice

Conditions Treated:

Acute Respiratory Distress Syndrome, COPD, Deep Vein Thrombosis (DVT), Emphysema, Pneumonia, Pulmonary Embolism

Research Interest:

Acute respiratory distress syndrome, Lung mechanics, Signal processing, Lung imaging



Truwit JD, Badesch D, Savage A, Shelton M.  Vibrio Vulnificus Bacteremia with Endocarditis. So. Med. J. 80 (11):1457-1459, 1987

Truwit JD, Brigham KL, Bernard GR.  Chest Pain in an Otherwise Asymptomatic Woman. Primary Cardiol. 14:67-74, 1988

Truwit JD, Jacobs JK, Newman JH, Dyer EL.  Anterior Mediastinal Mass Following Pneumonectomy. Chest. 94:173-174, 1988

Truwit JD, Marini JJ.  Evaluation of Thoracic Mechanics in the Ventilated Patient. Part 1: Primary Measurements.  J. Crit. Care 3(2): 133-150, 1988.

Truwit JD, Marini JJ.  Evaluation of Thoracic Mechanics in the Ventilated Patient. Part 2: Applied Mechanics. J. Crit. Care 3(3): 199-213, 1988

Marini JJ, Crooke PS, Truwit JD.  Determinants and Limits of Pressure-Preset Ventilation: A Mathematical Model of Pressure Control.  J Appl Physiol, 67(3): 1081-1092, 1989

Jabour ER, Rabil DM, Truwit JD, Rochester DF, Evaluation of a New Weaning Index, Based on Gas Exchange, Tidal Volume and Effort.  Am. Rev. Respir. Dis. 144(3): 531-537, 1991

Tribble CG, Kern JA, Findley LJ, Daniel TM, Truwit JD, Rose CE, Lewis BF, Kron IL.  First Single Lung Transplant in Virginia.  Virginia Medical Quarterly, 118(3):166-7, 1991

Rayburn DB, Januszkiewicz AJ, Ripple GR, Truwit JD, Summey HF, Young TR, Klimasauskas CC, Lee JM, Snapper JR, Identification of Mediator Specific Cardiovascular Waveforms Using a Back Propagation Neural Network.  Neural Networks 4:525-530, 1991

Truwit JD, Lamb VJ, Marini JJ.  Validation of a Technique to Assess Maximal Inspiratory Pressure in Poorly Cooperative Patients. Chest, 102 (4):1216-19, 1992

Kron IL, Tibble CG, Kern JA, Daniel TM, Rose CE, Truwit JD, Blackbourne MD, Bergin JD.  Successful Transplantation of Marginally Acceptable Thoracic Organs.  Ann Surg, 217(5):518-522, discussion 522-524, 1993

Burns SM, Burns JE, Truwit JD.  Comparison of Five Clinical Wean Indices:  BWAP, WI, Fx/Vt, CROP and NIP.  Am J Crit Care, 3(5):342-352, 1994

Stridor D, Turner D, Egloff MB, Burns SM, Truwit JD.  Stacked Inspiratory Spirometry Reduces Pulmonary Shunt in Patients After Coronary Artery Bypass.  Chest, 106(2):391-395, 1994

Daniel TM., Chan BB., Bhaskar V, Parekh JS,  Walters PE, Reeder J. and Truwit JD. Lung Volume Reduction Surgery: Case Selection, Operative Technique and Clinical Results.  Annals of Surgery, 223(5):526-531,  discussion 532-3, 1996

Burns SM, Marshall M, Burns JE, Ryan B, Wilmoth D, Carpenter R, Aloi, A, Wood M and Truwit JD.  Design, Testing and Results of an Outcomes Managed Approach to Patients Requiring Prolonged Ventilation.  Am J Crit Care 7(1):45-57, quiz 58-9, 1998

Burns SM, Spillman M, Wilmoth D, Carpenter R, Turrentine B, Wiley B, Marshall M, Martens S, Burns JE, Truwit JD.  Are Frequent Inner Cannula Changes Necessary?:  A Pilot Study.  Heart and Lung 27(1):58-62, 1998

de Lange EE, Mugler JP, Brookeman JR, Knight-Scott J, Truwit JD, Teates CD, Daniel TM, Bogorad PL, Cates GD.  Lung Air Spaces:  MR Imaging Evaluation with Hyperpolarized 3HE Gas1. Radiology, 210:851-857, 1999

Teates CD, Brookeman JR, Daniel TM, Truwit JD, Parekh JS, Mugler JP, de Lange EE.  The Stripe Sign:   Correlation of Radionuclide Ventilation and Perfusion with He-3 Magnetic Resonance Lung Imaging.  Clinical Nuclear Medicine, 24(10):747-750, 1999

Bowen CP, Whitney LR, Truwit JD, Durbin CG and Moore MM.  Comparison of Safety and Cost of Percutaneous Versus Surgical Tracheostomy.  Am Surg.  67(1):54-60, 2001 

Burns SM, Carpenter R, Truwit JD.  Report on the Development of a Procedure to Prevent Placement of Feeding Tubes into the Lungs Using End-Tidal CO2 (ETCO2) Measurements.  Crit Care Med. 29(5):936-9, 2001

Salerno M, de Lange EE, Altes TA, Truwit JD, Brookeman JR, Mugler JP.  Emphysema: Hyperpolarized Helium 3 Diffusion MR Imaging of the Lungs Compared With Spirometric Indexes--Initial Experience.  Radiology 222 (1): 252-60, 2002

Betadpur, P, Truwit JD. Capnography and gastric tube placement.  Ed. Jaffe, M. Clinical use of Capnography, American Journal of Respiratory and Critical Care Medicine, April 2002, 165: A791

Barakat H, Truwit JD.  Radial Artery “Mycotic” Pseudoaneurysm Occurring After Arterial Line Placement: Case Report and Review of the Literature, Clinical Pulmonary Medicine Volume 10, Number 5, 289-294, Sept-Oct 2003

Burns S, Earven S, Fisher C, Lewis R, Merrell P, Schubart Jane, Truwit JD, Bleck T.  University of Virginia Long Term Mechanical Ventilation Team.  Implementation of an Institutional Program to Improve Clinical and Financial Outcomes of Mechanically Ventilated Patients:  One Year Outcomes and Lessons Learned, Critical Care Medicine 31(12):2752-2763, 2003

Truwit JD.  Viewpoints to Liberation From Mechanical Ventilation, Chest 123 (6): 1779-1780, 2003

Mascolo MC, Truwit JD.  Role of Exercise Evaluation in Restrictive Lung Disease:  New Insights between March 2001 and February 2003, Curr Opin Pulm Med 9 (5): 408-10, 2003

Truwit JD, Bernard GR.  Noninvasive Ventilation—Don’t Push too Hard, New Engl J Med 350 (24): 2512-2515, 2004

Rizvi K, Deboisblanc BP, Truwit JD, Dhillon G, Arroliga A, Fuchs BD, Gutapalli KK, Hite D, Hayden D.   NIH/NHLBI ARDS Clinical Trials Network.  Effect of Airway Pressure Display on Interobserver Agreement in the Assessment of Vascular Pressures in Patients with Acute Lung Injury and Acute Respiratory Distress Syndrome, Crit Care Med 33 (1): 98-103; discussion 243-4, 2005

Grinnan D, Truwit, JD. Clinical Review:  Respiratory Mechanics in Spontaneous and Assisted Ventilation, Critical Care 9 (5): 472-84, 2005

Burns SM, Carpenter R, Blevins C, Bragg S, Marshall M, Browne, L, Perkins M, Bagby R, Blackstone K, Truwit JD.  Detection of inadvertent airway intubation during gastric tube insertion: Capnography versus a colorimetric carbon dioxide detector.  Am J Crit Care. Mar;15(2):188-95, 2006.

Comparison of Two Fluid-Management Strategies in Acute Lung Injury The National Heart, Lung, and Blood Institute Acute Respiratory Distress Syndrome (ARDS) Clinical Trials Network.  New Engl J Med 354(24):2564-2575, 2006

Pulmonary-Artery versus Central Venous Catheter to Guide Treatment of Acute Lung Injury The National Heart, Lung, and Blood Institute Acute Respiratory Distress Syndrome (ARDS) Clinical Trials Network. New Engl J Med 354(21):2213-2224, 2006

Koenig, SM and Truwit JD.  Ventilator-associated pneumonia: diagnosis, treatment, and prevention.  Clin Microbiol Rev.  Oct;19(4):637-57, 2006

McGown JE, Truwit JD, Cipriano P, Howell RE, VanBree M, Garson A JR, Hanks JB.  Operating Room Efficiency and Hospital Capacity:  Factors Affecting Operating Room Use During Maximum Hospital Census. Journal of the American College of Surgeons 204: 865-872, 2007

Hedrick T, Schulman A, McElearney S, Smith R, Swenson B, Evans H, Truwit J, Scheld WM, Sawyer R. Outbreak of resistant Pseudomonas aeruginosa infections during a quarterly cycling antibiotic regimen. Surgical Infections 2008;9:139-152.

Morris PE, Papadakos P, Russell JA, Wunderink R, Schuster DP, Truwit JD, Vincent JL, Bernard GR. A double-blind placebo-controlled study to evaluate the safety and efficacy of L-2-oxothiazolidine-4-carboxylic acid in the treatment of patients with acute respiratory distress syndrome. Critical Care Medicine 2008;36:782-788.

Thompson B, Orme J, Zheng H, Luckett P, Truwit J, Willson D, et al. Multicenter validation of a computer-based clinical decision support tool for glucose control in adult and pediatric intensive care units. J Diabetes Sci Technol 2008;2:357-68.

Enfield KB, Truwit JD. The purpose, composition, and function of an institutional review board: balancing priorities.  Respiratory Care 2008;53:1330-1336.

Morris A, Orme Jr J, Truwit J, Steingrub J, Grissom C, Lee K, et al. A replicable method for blood glucose control in critically ill patients. Crit Care Med 2008;36:1787–95.

Li G, Yilmaz M, Kojicic M, Fernandez-Perez E, Wahab R, Huskins WC, Afessa B, Truwit JD, Gajic O.  Outcomes of critically ill patient with influenza virus infection.  J Clinic Virology  2009 Nov;46(3):275-8

Sterman DH, Mehta AC, Wood DE, Mathur PN, McKenna RJ, Ost DE, Truwit JD, Diaz P, Wahidi MM, Cerfolio R, Maxfield R, Musani AI, Gildea T, Sheski F, Machuzak M, Haas AR, Gonzalez HX, Springmeyer SC.  A Multicenter pilot study of a bronchial valve for the treatment of severe emphysema.  Respiration 2010:79(3):222-233

Enfield K, Gammon S, Floyd J, Falt C, Patrie J, Platts-Mills T, Truwit JD, Shim YM.  Six-Minute walk distance in patients with severe end-stage COPD.  Journal of Cardiopulmonary Rehabilitation and Prevention 2010;30:195-202

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