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David Brenin, MD

David Brenin, MD

Practice Area: Cancer, Women's Health Department: Surgery Division: Surgical Oncology Title: Associate Professor of Surgery ABMS Certification: Surgery, 1998

Contact Information

P.O. Box 800709 Charlottesville, VA 22908-0709 Phone: 434.924.2625 | Fax: 434.982.6534 Other Locations:
UVA Breast Surgery Program at Culpeper
Breast Care Center
UVA Specialty Care—Culpeper
Zion Crossroads Primary and Specialty Care


David Brenin, MD, FACS is chief of breast surgery, co-director of both the UVA Breast Care Program and the High-Risk Breast and Ovarian Cancer Clinic and is associate professor of surgery at UVA’s School of Medicine. His clinical practice areas include breast cancer in women and mastectomy procedures and his research interest is primarily immunotherapy.

In addition to his clinical functions, Dr. Brenin is the leader of UVA Cancer Center’s weekly multidisciplinary breast conference, chairman of the Commission on Cancer Committee at UVA Cancer Center and member of the Focused Ultrasound Surgery Foundation’s Fellowship Advisory Committee and grant review committee. He serves on the UVA Health System Tumor Registry Advisory Board and UVA Human Immune Therapy Center Committee. Dr. Brenin is also course co-director for the regional continuing medical education conference “Advances in Comprehensive Breast Care and Imaging,” in Charlottesville and is on the planning committee of the UVA Cancer Center educational series.

His professional affiliations include Fellow of the American College of Surgeons, Society of Surgical Oncology, Eastern Cooperative Oncology Group (breast team CORE committee member), Albemarle County Medical Society and the Medical Society of Virginia, among others.

A native of New York, Dr. Brenin graduated from Columbia Presbyterian in 2002. He earned his MD at New York Medical College in 1990 and completed his residency in surgery and fellowships in breast surgery at Northwestern University. Dr. Brenin’s wife, Dr. Christiana Brenin, also treats breast cancer at UVA Cancer Center and earned her medical degree, served her residency and completed her fellowships at the same locations as her husband, David.

Outside the hospital, Dr. Brenin enjoys spending time with his wife and two daughters as well as hiking, skiing, scuba diving, playing with the family dog and maintaining an extraordinary fish tank.


  • Castle Connolly's Top Doctors™ (2013)
  • Patients' Choice Award (2012, 2014)    
  • Compassionate Doctor Recognition (2012, 2014)    


View all publications on PubMed