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David Brenin, MD

David Brenin, MD

Practice Area: Cancer, Women's Health Department: Surgery Division: Surgical Oncology Title: Associate Professor of Surgery ABMS Certification: Surgery, 1998

Contact Information

Primary Location:
Breast Care Center
Suite 1101 1300 Jefferson Park Ave. Charlottesville, VA 22903 Phone: 434.924.2625 | Fax: 434.982.6534 Other Locations:
UVA Breast Surgery Program at Culpeper
UVA Specialty Care—Culpeper
Zion Crossroads Primary and Specialty Care


Watch this video about Dr. David Brenin, MD

David Brenin, MD, FACS is chief of breast surgery, co-director of both the UVA Breast Care Program and the High-Risk Breast and Ovarian Cancer Clinic and is an associate professor of surgery at UVA’s School of Medicine. His clinical practice specializes in the treatment of breast cancer, and benign diseases of the breast. Dr. Brenin is a fellowship trained breast surgeon and is an expert on surgical procedures involving the breast including lumpectomy, sentinel node biopsy, axillary dissection, nipple sparing mastectomy and IORT. His primary research interests include focused ultrasound ablation of breast tumors and immunotherapy.

In addition to his clinical functions, Dr. Brenin is the leader of UVA Cancer Center’s weekly multidisciplinary breast conference, chairman of the Commission on Cancer Committee at UVA Cancer Center and member of the Focused Ultrasound Surgery Foundation’s Fellowship Advisory Committee and grant review committee. He serves on the UVA Health System Tumor Registry Advisory Board and UVA Human Immune Therapy Center Committee. Dr. Brenin is also course co-director for the regional continuing medical education conference “Advances in Comprehensive Breast Care and Imaging,” in Charlottesville and is on the planning committee of the UVA Cancer Center educational series.

His professional affiliations include Fellow of the American College of Surgeons, Society of Surgical Oncology, Eastern Cooperative Oncology Group (breast team CORE committee member) and the American Society of Breast Surgeons. 

A native of New York, Dr. Brenin graduated from SUNY Binghamton in 1986. He earned his MD at New York Medical College in 1990 and completed his residency in surgery and fellowships in breast surgery at Northwestern University. Dr. Brenin’s wife, Dr. Christiana Brenin, also treats breast cancer at UVA Cancer Center and earned her medical degree, served her residency and completed her fellowships at the same locations as her husband, David.

Outside the hospital, Dr. Brenin enjoys spending time with his wife and two daughters as well as hiking, skiing, scuba diving, playing with the family dog and maintaining an extraordinary fish tank.

Watch this video to learn more about Dr. Brenin.


  • Castle Connolly's Top Doctors™ (2013)
  • Patients' Choice Award (2012, 2014)    
  • Compassionate Doctor Recognition (2012, 2014)


View all publications on PubMed