Women's Health Trials

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Reproductive Hormone Study for Adult Women

IRB/UVa Tracking #: 14067

Principal Investigator: McCartney Christopher,

Contact: Melissa Gilrain

Tel: 4342436911

Email: mg7zb@hscmail.mcc.virginia.edu

Study Description

The Center for Research in Reproduction is seeking women with and without PCOS (between 18 – 35 years old). The goal of this study is to determine whether testosterone (a male hormone) helps control the secretion of gonadotropin-releasing hormone (GnRH) while awake and while asleep. (GnRH controls the secretion of hormones by the pituitary gland, and pituitary hormones control the production of female hormones from the ovaries.) This study involves three outpatient visits, and two 17-hour overnight admissions to the Clinical Research Unit (CRU). Volunteers will take an investigational medication for about 28 days. Sleep will be monitored during the overnight admissions. Study-related exams, tests, and medications are provided free of charge. For more information please contact pcos@virginia.edu