Xenon MRI and Advair in COPD
IRB/UVa Tracking #: 18667
Principal Investigator: Shim Yun, M
Contact: Rachel Dieterich
Official Trial Title: Xe129 MRI of the Lung: A New Technology to Assess Treatment for COPD
Compensation: Compensation for study completion is provided
The Radiology Research department seeks adults with chronic obstructive lung disease (COPD) or a history of smoking for a research study. The purpose of the study is to see whether hyperpolarized xenon-129 MRI can detect changes in the lungs after treatment with Advair, an FDA-approved treatment for COPD.
The study involves inhaled hyperpolarized xenon MRI, perfusion MRI, spirometry, 6-minute-walk test, electrocardiogram (ECG), physical exam, chest CT, blood draw, and completion of questionnaires.
The study requires one to three study visits over a three-month period, each lasting approximately two to three hours.
Study-related drugs and tests including pulmonary function tests, chest CT, physical exam, ECG, perfusion MRI with gadolinium, and xenon MRI (insert exams, tests and experimental medication) provided free of charge