A Phase IB and Randomized Phase II Trial of Megestrol Acetate with or without Ipatasertib in Recurrent or Metastatic Endometrioid Endometrial Cancer

UVA Tracking #
302111
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Official Trial Title
NRG-GY028: A PHASE IB AND RANDOMIZED PHASE II TRIAL OF MEGESTROL ACETATE WITH OR WITHOUT IPATASERTIB IN RECURRENT OR METASTATIC ENDOMETRIOID ENDOMETRIAL CANCER
Study Description

The University of Virginia seeks adults ages 18 and over with recurrent or metastatic endometrioid endometrial cancer. This study is studying 2 oral drugs: (1) hormonal agent and (2) targeted therapy agent

You may be eligible for this study if:
- You have grade 1 or 2 recurrent or metastatic endometrioid endometrial cancer
- You may have received prior lines of treatment (chemotherapy, radiation, immunotherapy, etc)
- You have measurable disease on Computed Tomography (CT) or Magnetic Resonance Imaging (MRI)

This study involves Computed Tomograhpy (CT) exams, blood sample collection, and physical examination.
Study-related procedures that are being done beyond your standard of care will be provided at no cost to you or your insurance.
Additional Information can be found here: Study Details | Testing the Addition of the AKT Inhibitor, Ipatasertib, to Treatment With the Hormonal Agent Megestrol Acetate for Recurrent or Metastatic Endometrial Cancers | ClinicalTrials.gov

Compensation

No Compensation