A Phase II Trial of Rituximab in Myasthenia Gravis (NN103)

IRB/UVA Tracking #
17379
Principal Investigator
Burns Ted,
Contact First Name

Stephanie

Contact Last Name

Lowenhaupt

Contact Email
Contact Phone
Official Trial Title
A Phase 2 Trial of Retuximab in Myasthenia Gravis
Study Description

The Universtiy of Virginia is currently looking for people with Myasthenia Gravis (MG) for a research study conducted by the Network for Excellence in Neuroscience Clinical Trials (NeuroNEXT). We are working with Dr. Richard J. Nowak at Yale University School of Medicine who is the Protocol Principal Investigator and leading this national study. The National Institute of Neurological Disorders and Stroke (NINDS), a division of the National Institutes of Health (NIH), is supporting this trial.

The purpose of the research study is to learn whether rituximab vs. placebo is a safe therapy and helpful for people with MG. Fifty people will be enrolled and will take part in the study for 52 weeks. 25 participants will receive rituximab and 25 participants will receive placebo (an inactive salt-water substance). Neither participants nor the study team will know if who is receiving the study drug or the placebo. Participants must have a diagnosis of generalized MG, be at least 21 years old, and be taking prednisone in order to be in the study. This study is actively enrolling participants.

To learn more information, please visit http://www.neuronext.org or contact Stephanie Lowenhaupt at the University of Virginia by phone 434-982-6961 or email sal3q@virginia.edu.

Compensation

No Compensation