Reproductive Hormone Study for Adult Women

IRB/UVA Tracking #
Principal Investigator
Christopher McCartney
Melissa Gilrain
Contact Phone
Official Trial Title
Influence of hyperandrogenemia on the sleep-associated slowing of follicular LH frequency in adult polycystic ovary syndrome (CRM004)
Study Description

The Center for Research in Reproduction is seeking women with and without PCOS (between 18 – 35 years old). The goal of this study is to determine whether testosterone (a male hormone) helps control the secretion of gonadotropin-releasing hormone (GnRH) while awake and while asleep. (GnRH controls the secretion of hormones by the pituitary gland, and pituitary hormones control the production of female hormones from the ovaries.)

This study involves three outpatient visits, and two 17-hour overnight admissions to the Clinical Research Unit (CRU). Volunteers will take an investigational medication for about 28 days. Sleep will be monitored during the overnight admissions.

Study-related exams, tests, and medications are provided free of charge. For more information please contact