Research study for the abnormal movement (dyskinesia) symptoms of Parkinson’s Disease

IRB/UVA Tracking #
Principal Investigator
William (Jeff) J Elias
Matthew Patterson
Contact Email
Contact Phone
Official Trial Title
A Pivotal Clinical Trial of the Management of the Medically- Refractory Dyskinesia Symptoms or Motor Fluctuations of Advanced Idiopathic Parkinson's Disease With Unilateral Lesioning of the Globus Pallidum Using the Exablate Neuro System
Study Description

The department of neurosurgery seeks men and women ages 30 and older with dyskinesia symptoms of Parkinson’s disease for a research study. The purpose of the study is to show whether or not focused ultrasound can be used to treat dyskinesia (abnormal movement) symptoms.

This study involves a screening visit followed by a focused ultrasound procedure and post-procedure visits at 1 Day, 1 week, 1 month, 3 month, 6 month, and 12 month. All participants will be randomized into either a placebo or treatment group and will not be told their group until the 3 month visit. Following the 3 month visit, participants in the placebo group will be given the option to have the actual procedure performed.

All study related procedures will be paid for by the clinical trial.


No Compensation