Research Study For Those With Articular Cartilage Defects In the Knee

IRB/UVA Tracking #
17371
Principal Investigator
Diduch David, R
Contact First Name

Kaitlyn

Contact Last Name

Shank

Contact Phone
Official Trial Title
A Phase 3 Prospective, Randomized, Partially Blinded Multi Center Study to Measure the Safety and Efficacy of NOVOCART® 3D, Compared to Microfracture in the Treatment of Articular Cartilage Defects”
Study Description

The University of Virginia, Department of Orthopaedic Surgery, is seeking adults with articular cartilage defects in the knee. The purpose of this study is to show if using an investigational tissue graft is better than the standard method of microfracture for the treatment of articular cartilage defects. This study will also document changes in knee pain and function after either surgery is performed.

The standard of care for treating articular cartilage defects in the knee is microfracture. This study is being done to observe if agraft is an efficient and more superior treatment option. For eligible participants, the defect will be treated with either microfracture or by using an investigational tissue graft.

This study involves 12 follow up visits over a 5 year period following surgery.

Study related clinic visits, research x-rays and MRI scans are provided free of charge. The study will also cover the costs of physical therapy that are not covered by your insurance up to $4,000 regardless of what study group you are in. You will be responsible for any copayments associated with the physical therapy.
Ages: 18-65

Compensation

: $800 or $850 (depending on which group you are randomized to)