The University of Virginia’s Department of Neurology is currently enrolling people who have suffered an acute ischemic stroke. The purpose of this study is to demonstrate the relationship between bacteria in the gut, inflammation and the injured brain. It has been established that bacteria in the gut play key roles in digestion, nutrition adsorption and immune response of the entire body. Human intestinal bacteria composition in the gut has been associated with several stroke risk factors including obesity, insulin resistance, diabetes and hypertension. We hope to link certain bacteria in the gut to specific stroke outcomes. This could lead to dietary interventions in the future to improve recovery after a stroke.
This study aims to enroll up to 300 patients. You may be eligible if you are an adult who has suffered an acute ischemic stroke within the last 72 hours and have not had a bowel movement.
This study involves providing a stool sample, the collection of neurological assessments (NIHSS – NIH stroke scale, and mRS – modified Rankin Scale), completing cognitive functioning tests called Cogstate assessments, and answering health and dietary related questions. There are two visits one at Baseline (time of enrollment) and the second at 90 days. Each visit will last approximately 30 minutes. These study-related assessments are provided free of charge.
Study participants will receive a $25 gift card for study completion.