Testosterone Replacement Therapy Options

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We can help you choose from the most commonly used TRT (testosterone replacement therapy) options.

Topical Testosterone Gels

You apply gels to the skin on a daily basis.

Advantages include:

  • Steady hormone levels due to daily dosing
  • High patient satisfaction
  • No needles

Disadvantages include:

  • More expensive than injections
  • The potential for transference of the gel to others (e.g., women and young children) through contact with your skin or clothes
  • Messiness of gel application
  • Potential skin irritation

Injectable Testosterone

Injections are administered into large muscles (usually the buttocks or thigh) on a weekly or biweekly basis  You can either come to the clinic for injections or learn to administer them yourself.

Advantages include:

  • Highly effective
  • High patient satisfaction
  • Low cost

Disadvantages include:

  • Increased fluctuation in testosterone levels compared to daily dosing options
  • The requirement for needles and possibly self-injection

Medications Without Testosterone

These may be advantageous in men who prefer not to take testosterone directly or for those who want to preserve their fertility. Some of these come in generic, low-cost form. They can also be used in combination with testosterone formulations.

Disadvantages generally include less of a rise in testosterone levels compared to testosterone-containing therapies.

Monitoring Your Treatment

While undergoing TRT, you’ll be monitored regularly (usually every 3-6 months) to confirm symptom control, measure your testosterone levels and check for potentially dangerous side effects.

The follow-up regimen usually consists of:

  • Physical exam every six months, including digital rectal exam to assess for signs of prostate enlargement and prostate cancer
  • Blood work every 3-6 months for testosterone levels and other hormones
  • Blood work every six months for lipids, hemoglobin and hematocrit and PSA (prostate-specific antigen)

If the desired effects aren’t achieved with your initial choice, we can try a different option to see if it’s a better fit for your health and lifestyle.