So hypertrophic cardiomyopathy is the most common genetic heart disease. It's caused by generally a mutation in one of the many contractile proteins in the heart, and what it leads to is, generally, too much heart muscle. Patients with hypertrophic cardiomyopathy may go their whole lives without any symptoms. Many experience chest pain and shortness of breath. Some can develop syncope or actually pass out from their fast heart rhythms, have palpitations from their fast heart rhythms. They may be offered an implantable cardioverter defibrillator. For patients who have severe symptoms that are refractory to standard medicines, they may be offered a myectomy which is actually surgery to cut out the thickest part of the heart muscle that's causing a lot of the problems in terms of their symptoms.