How Well Do You Know Your Heart? Part 3: Atherosclerosis Treatment Transcript There are many ways to treat atherosclerosis. Medication lowers cholesterol, stops clotting, and controls blood pressure. Catheters can help open the artery to improve blood flow without surgery. Surgery unblocks the artery or makes new routes for blood flow when catheters can't be used. At risk? Discuss screenings with your provider.