A phase 2, open-label, single-arm, multicohort, multicenter trial to evaluate the efficacy and safety of JCAR017 in adult subjects with relapsed or refractory indolent B-cell non-hodgkin lymphoma (NHL)

UVA Tracking #
HSR200067
Principal Investigator
Indumathy Varadarajan
Contact
Indumathy Varadarajan
Contact Phone
434.982.6406
Official Trial Title
A PHASE 2, OPEN-LABEL, SINGLE-ARM, MULTICOHORT, MULTICENTER TRIAL TO EVALUATE THE EFFICACY AND SAFETY OF JCAR017 IN ADULT SUBJECTS WITH RELAPSED OR REFRACTORY INDOLENT B-CELL NON-HODGKIN LYMPHOMA (NHL) (TRANSCEND FL)
Study Description

The University of Virginia Cancer Center seeks participants 18 years old or above to participate in a study that looks at a new treatment for follicular or marginal zone lymphoma that has not responded to or returned after previous treatments. The JCAR-017 treatment works on the T-cells in the body (part of the immune system).

Participation on this study involves up to 26 weeks. Participants are also required to take part in a 15-year long-term follow up study. Study-related tests and procedures and study drug will be covered by the study sponsor.

Additional information can be found here: https://clinicaltrials.gov/ct2/show/NCT04245839

Compensation

You will not receive compensation for this trial. o Reimbursement: You will receive up to $.54 per mile to cover travel expenses. You will also receive up to $175 for lodging if you live over 50 miles away.