When a phagocyte eats another cell, it’s like your neighbor moving in with you with all their belongings.
Cholesterol Disposal: A Cell’s Deathbed Instructions Could Be the Key
Roughly one million cells in your body die every second. These dead cells are then eaten by neighboring cells, who have to figure out what to do with all the cholesterol, fats, proteins and other components from the cells they just ate.
But they have help. UVA School of Medicine researchers just discovered that the dying cell gives deathbed instructions for what to do with the cholesterol.
Previously, scientists had targeted another molecule to prevent cells from becoming overloaded with cholesterol in people who had high levels of LDL cholesterol (the “bad” cholesterol). But that led to many side effects. This new discovery could lead to new medications that stimulate cholesterol transport and removal in a more natural way.
You take what you're given and you realize that you can either be a miserable soul or someone who blesses people.
From NICU to College: Savannah Tucker's Story
Savannah Tucker was born with a rare skull deformity called craniosynostosis, also known as clover leaf skull. At just days old, she was airlifted from West Virginia to UVA for care.
Over the next several years, Savannah underwent over 20 surgeries. Further diagnosed with additional conditions including hydrocephalus, stroke and cerebral palsy, her initial prognosis was grim; doctors warned her family that she might not ever be able to walk.
Savannah says she has grown up at UVA, receiving care from a team of doctors from neurosciences, plastic surgery and orthopedics.
Watch the video as Savannah reflects on her journey.
He had literally hundreds of dedicated UVA physicians, nurses and staff working around-the-clock to save his life.
Beating the Odds: Surviving a Car Crash & TBI
After a car accident, Grayson Kirby was flown to UVA, where doctors gave him less than a 10 percent chance of survival. Besides multiple broken bones, he had a severe traumatic brain injury (TBI). His crushed lungs were unable to provide him with enough oxygen, and even a ventilator couldn’t keep up.
Grayson lay in a coma, and his caregivers prepared his family for the worst.
As a last resort, one of his doctors decided to try ECMO, a machine that adds oxygen to the blood, doing the work his crushed lungs couldn’t. The machine kept him alive, but they still didn’t know if he’d survive his brain injury or ever be the same person again.