Costi Sifri

Costi Sifri, MD

Infectious Diseases and International Health
Primary Location:
Transplant Center

4th Floor

1300 Jefferson Park Ave.

Charlottesville, VA 22903



ABMS Certification:
Internal Medicine, 1998; Infectious Disease, 2000
Research Interests:

Bacterial pathogenesis, healthcare-associated infections, hospital epidemiology, host-pathogen interactions, innate immunity, Legionella, multidrug resistance, Staphylococci

Clinical Practice:
Meningitis (Bacterial and Viral)- Pediatric, Gonorrhea, Hepatitis A, Hepatitis B, Hepatitis C, HIV & AIDS, Influenza, Lyme Disease, Onychomycosis, Bone Infection (Osteomyelitis), Tuberculosis (TB), Genital Warts, Pneumonia, MRSA, Infectious Diseases, STD Testing



As the director of hospital epidemiology at UVA Health, Costi Sifri, MD, works to prevent infections that occur as a consequence of receiving medical care. He is also the medical director of the immunocompromised infectious disease program at UVA, which is focused on providing care to patients with infectious diseases following organ or stem cell transplantation or who have cancer.

Born and raised in Portland, Oregon, Dr. Sifri received his medical degree from the University of Rochester, completed internal medicine residency at the University of Pennsylvania, and clinical and research fellowships in infectious disease at the Massachusetts General Hospital, Brigham and Women’s Hospital, and Harvard Medical School. He joined UVA in 2004.

Dr. Sifri’s research interests include exploring the transmission of multidrug-resistant organisms (MDROs) in the healthcare environment and understanding the clinical consequences and prevention of healthcare-associated infections. He has helped lead efforts at UVA Health to reduce transmission of healthcare-associated pathogens, supervised infection prevention education and quality improvement efforts, and led institutional responses to high-consequence emerging microbial pathogens, including carbapenem-resistant Enterobacteriaceae, Ebola virus, and COVID-19.

In his free time, Dr. Sifri enjoys spending time outside with his three children and trail running in the mountains with his wife.

  • 2011-2020 Best Doctors in America® List

  • 2015 Best Bedside Manner Award, Our Health Magazine; First place, Infectious Diseases

  • 2018 Best Bedside Manner Awards, Our Health Charlottesville and Shenandoah Valley Magazine; Second Place, Infectious Disease


University of Rochester, 1995
Internal Medicine, Hospital of the University of Pennsylvania
Infectious Disease, Massachusetts General Hospital and Brigham and Women's Hospital