David Brenin

David Brenin, MD

Surgical Oncology
Primary Location:
Breast Care Center

Suite 200

652 Peter Jefferson Parkway

Charlottesville, VA 22911

Secondary Locations:


ABMS Certification:
Surgery, 1998
Research Interests:

Breast Surgery|Focused Ultrasound Ablation of Breast Tumors

Clinical Practice:
Breast Cancer Care, Lumpectomy, Mastectomy, Women's Health



David Brenin, MD, FACS is the M.C. Wilhelm Professor in diseases of the breast and Chief of the Division of Breast and Melanoma Surgical Services at UVA’s School of Medicine. His clinical practice specializes in the treatment of breast cancer, and benign diseases of the breast. Dr. Brenin is a fellowship trained breast surgeon and is an expert on surgical procedures involving the breast including lumpectomy, sentinel node biopsy, axillary dissection, nipple sparing mastectomy and IORT. His primary research interests include focused ultrasound ablation of breast tumors and immunotherapy.

In addition to his clinical functions, Dr. Brenin is the leader of UVA Cancer Center’s weekly multidisciplinary breast conference, chairman of the Commission on Cancer Committee at UVA Cancer Center and member of the Focused Ultrasound Surgery Foundation’s Fellowship Advisory Committee and grant review committee. He serves on the UVA Health Tumor Registry Advisory Board and UVA Human Immune Therapy Center Committee. Dr. Brenin is also course co-director for the regional continuing medical education conference “Advances in Comprehensive Breast Care and Imaging,” in Charlottesville and is on the planning committee of the UVA Cancer Center educational series.

His professional affiliations include Fellow of the American College of Surgeons, Society of Surgical Oncology, Eastern Cooperative Oncology Group (breast team CORE committee member) and the American Society of Breast Surgeons. 

A native of New York, Dr. Brenin graduated from SUNY Binghamton in 1986. He earned his MD at New York Medical College in 1990 and completed his residency in surgery and fellowships in breast surgery at Northwestern University. Dr. Brenin’s wife, Dr. Christiana Brenin, also treats breast cancer at UVA Cancer Center and earned her medical degree, served her residency and completed her fellowships at the same locations as her husband, David.

Outside the hospital, Dr. Brenin enjoys spending time with his wife and two daughters as well as hiking, skiing, scuba diving, playing with the family dog and maintaining an extraordinary fish tank.

  • 2014, 2012 Patients' Choice Award  
  • 2014, 2012 Compassionate Doctor Recognition
  • 2013 Castle Connolly's Top Doctors™ 
  • 2017-2020 Best Doctors in America® List


New York Medical College, 1990
Surgery, Northwestern University
Breast Surgery, Northwestern University