James M Larner

James M Larner, MD

General Radiation Oncology Appointment
Radiation Oncology
Call 434.924.9333
Primary Location:
Emily Couric Clinical Cancer Center

1240 Lee St.

Charlottesville, VA 22903

Secondary Locations:
ABMS Certification:
Medical Oncology; Hematology; Radiation Oncology
Research Interests:

Neuro-oncology, DNA damage-sensing pathways

Clinical Practice:
Lung Cancer, Glioblastoma Brain Tumor Treatment, Multiple Myeloma, Leukemia, Tomotherapy, Lymphoma, Blood Cancers & Disorders

Chair, Department of Radiation Oncology


In addition to a leadership role as chair of Radiation Oncology, Larner serves the Cancer Center in a number of critical positions, including co-leader of the Genetics and Epigenetics Program, chair of the Cancer Center Protocol Review and Monitoring Committee, Chair of the School of Medicine Research Advisory Committee. He earned his medical degree at UVA in 1980 and has been here for the last 25 years.

Spending an estimated 60% of his time on research and 40% in the clinic, Larner is dedicated to both key areas of the Cancer Center. His research interests include DNA damage-sensing pathways, radiation injury, radiosensitizers (drugs that make tumor cells more responsive to radiation therapy), prostate cancer, gliomas (brain tumors) and lung cancer. Larner’s clinical interests include cancer of the brain, central nervous system, thorax and lungs.

When he is not in the lab or clinic, Larner plays racquet sports, restores houses and travels. He claims he spoils his son by allowing him to select where they travel each year. Some of Larner’s favorite destinations include Mauritius, Thailand, Andora, Uruguay and Japan.



  • 2015 One of America's Top Cancer Doctors, Newsweek®
  • 2015 Bedside Manner Award, Our Health Magazine; Third place
  • 2012 Best Doctors in America® List
University of Virginia, 1980
Internal Medicine, Thomas Jefferson University Hospital
Hematology, Thomas Jefferson University Hospital; Medical Oncology, Albert Einstein College of Medicine; Radiation Oncology, Thomas Jefferson University Hospital; Radiation Oncology, University of Virginia