Matthew M. Miller, MD, PhD

Matthew M. Miller, MD, PhD, is a physician-scientist with fellowship training in breast imaging and PhD training in breast cancer biochemistry and cell biology. He oversees UVA’s Contrast-Enhanced Mammography (CEM) Program.

Dr. Miller is investigating ways to improve the sensitivity and specificity of breast imaging. The goal is to find breast cancer at an earlier, more treatable stage, while reducing the number of benign biopsies and the extent of overdiagnosis. 

In particular, Dr. Miller is studying the application of artificial intelligence techniques (such as machine learning and deep learning) to breast imaging. He’s hoping to discover new imaging biomarkers that may enhance our ability to accurately characterize breast imaging findings at a molecular level, even before they are biopsied.

Dr. Miller’s other research has included:

• Investigating protein interactions that underlie breast cancer metastasis
• Evaluating new MRI techniques to monitor breast tumor response to novel chemotherapies
• Assessing the patient experience with new breast imaging technologies like CEM that are used for breast cancer screening
• Quantifying the impact of the COVID-19 pandemic on patient participation in breast cancer screening