Cancer Biology Program (CBIO) Members

 

Huiwang Ai, PhD
Associate Professor, Chemistry
Protein engineering to image specific bioactivities in cells and in vivo

Timothy Bender, PhD
Professor, Microbiology, Immunology, and Cancer Biology
c-Myb dependent gene networks in lymphocyte development and ALL

Amy Bouton, PhD
Professor, Microbiology, Immunology, and Cancer Biology
Proliferation and adhesion pathway drivers of breast cancer

John Bushweller, PhD
Professor, Molecular Physiology and Biological Physics
Chemical and structural biology focused on transcription factor drivers in cancer

David Cafiso, PhD
Professor, Chemistry
Reversible protein and membrane interactions controlling cell-signaling and membrane trafficking, molecular mechanisms of membrane transport

Steven Caliari, PhD
Assistant Professor of Biomedical Engineering
Design of 3D biomaterials as cellular microenvironments for applications in cancer, fibrosis, and tissue regeneration

James Casanova, PhD
Professor, Cell Biology
Molecular regulation of cell motility and metastasis

Linda Columbus, PhD
Associate Professor, Chemistry
Biophysical methods to investigate the function, structure and dynamics of membrane proteins involved in pathogen-host interactions. Use of molecular understanding of Opa mediated liposome: cellular interactions to design functionalized targeted liposomes for drug delivery and cell manipulation

Zygmunt Derewenda, PhD
Professor, Molecular Physiology and Biological Physics
Structural biology of proteins involved in smooth muscle regulation and cancer

Sepideh Dolatshahi, PhD
Assistant Professor, Biomedical Engineering
Systems immunology, systems biology of immune regulation and immunotherapies, regulation and regulatory roles of glycosylation in cancer

Andrew Dudley, PhD
Associate Professor, Microbiology, Immunology, and Cancer Biology
Tumor microenvironment and mechanisms of tumor neovascularization

Edward Egelman, PhD
Professor, Biochemistry and Molecular Genetics
Structural biology of macromolecular complexes using cryo-EM

Loren Erickson, PhD
Associate Professor, Microbiology, Immunology, and Cancer Biology
Antibodies as biomarkers of disease

Sarah Ewald, PhD
Assistant Professor, Microbiology, Immunology, and Cancer Biology
Innate immune regulation of cancer progression and cancer cachexia

Mohammad Fallahi-Sichani, PhD
Assistant Professor, Biomedical Engineering
Systems biology approaches to understand the mechanisms of cancer drug response and resistance

Jay Fox, PhD
Professor, Microbiology, Immunology, and Cancer Biology
Microenvironment of dense breasts and role of exosomes in host stem cell modulation

Cassandra Fraser, PhD
Professor, Chemistry
Materials chemistry focused on the development of novel biosensor molecules

Zheng Fu, PhD
Associate Professor, Pharmacology
Role of primary cilia as a novel mechanism regulating cancer drug resistance and sensitivity

Daniel Gioeli, PhD
Associate Professor, Microbiology, Immunology, and Cancer Biology
Mechanistic understanding of the cell signaling network that contribute to cancer progression and resistance to therapy

Adam Goldfarb, MD, PhD
Professor, Pathology
Erythroid and megakaryocytic differentiation to identify new approaches toward treatment of anemias and thrombocytopenias in cancer patients and to shed light on the pathogenesis of megakaryocytic leukemias.

David Green, PhD
Associate Professor, School of Engineering and Applied Sciences, Department of Materials Science
Synthesis of well-defined nanoparticles, their dispersion into polymer solutions and melts, and their use for detection and therapeutics

Thurl Harris, PhD
Associate Professor, Biochemistry and Molecular Genetics
Signaling and enzymes in lipid metabolism

Michael Hilinski, PhD
Assistant Professor, Chemistry
Synthetic organic and medicinal chemistry focused on potential anticancer small molecules

Ku-Lung Hsu, PhD
Assistant Professor, Chemistry
Chemical biology and proteomics focused on discovery of new immuno-oncology targets

Donald Hunt, PhD
Professor, Chemistry
Class I MHC phosphopeptides for immunotherapy of multiple cancers and the viruses that cause them

Kevin Janes, PhD
Associate Professor, Biomedical Engineering
Cancer systems biology approaches to solid tumors

David Kashatus, PhD
Associate Professor, Microbiology, Immunology, and Cancer Biology
The regulation of mitochondrial dynamics by oncogenic signaling pathways and the role of mitochondrial dynamics in tumorigenesis

Dean Kedes, MD, PhD
Associate Professor, Microbiology, Immunology, and Cancer Biology
Kaposi’s sarcoma virus – tumorigenesis, immune responses and viral immune evasion mechanisms

John Lazo, PhD
Professor, Pharmacology
Chemical biology of protein tyrosine phosphatases, drug discovery, high throughput and high content screening, experimental therapeutics and molecular pharmacology

Matthew Lazzara, PhD
Associate Professor, Biomedical Engineering
Cancer cell signaling, systems biology approaches for the rational design of combination therapy for cancer

Ulrike Lorenz, PhD
Associate Professor, Microbiology, Immunology, and Cancer Biology
Regulatory Mechanisms of T cell function with a focus on CAR T cell immunotherapy

Kevin Lynch, PhD
Professor, Pharmacology
Discovering inhibitors of sphingosine 1-phosphate synthesis and transport

Wladek Minor, PhD
Professor, Molecular Physiology and Biological Physics
Structural biology focused on structure-function relation and data mining

Golam Mohi, PhD
Professor, Biochemistry and Molecular Genetics
Molecular mechanisms and therapeutic development in myeloid neoplasms

Christopher Moskaluk, MD, PhD
Professor, Pathology
Genomic, transcriptomic and proteomic analysis of primary cancer specimens for biomarker discovery, and validation of tissue-based biomarkers by in situ analytic techniques and tissue microarray construction of population cohorts

Kristen Naegle, PhD
Associate Professor, Biomedical Engineering
Computational systems biology approaches to understand the role of tyrosine phosphorylation in proteins and protein networks

Robert Nakamoto, PhD
Professor, Molecular Physiology and Biological Physics
Elucidation of the multiple-drug transporter P-glycoprotein mechanism in resistance to cancer chemotherapy

Jason Papin, PhD
Professor, Biomedical Engineering
Metabolic networks in cancer

Kwon-Sik Park, PhD
Associate Professor, Microbiology, Immunology, and Cancer Biology
Functional genetics focused lung cancer

Marcos Pires, PhD
Associate Professor, Chemistry
Chemical biology and immunology focused on targeting tumors via infectious agents

Rebecca Pompano, PhD
Assistant Professor, Chemistry
Bioanalytical chemistry and microfluidics to reveal dynamics in the lymph node

Benjamin Purow, MD
Professor, Neurology
Molecular basis of Notch signaling; potential therapeutic targets for malignant gliomas

Kodi Ravichandran, PhD
Professor, Microbiology, Immunology, and Cancer Biology
Apoptotic cell clearance mechanisms in health and disease

Gustavo Rohde, PhD
Associate Professor, Biomedical Engineering
Objective and quantitative modeling of data from imaging and other types of sensors

Melanie Rutkowski, PhD
Assistant Professor, Microbiology, Immunology, and Cancer Biology
Tumor microenvironment, molecular and cellular mediators of tumor metastasis, tumor growth, and response to therapy

Ira Schulman, PhD
Associate Professor, Pharmacology
Transcriptional regulation of lipid metabolism focusing on the control of inflammation and cell proliferation

Gloria Sheynkman, PhD
Assistant Professor, Molecular Physiology and Biological Physics
Proteoform systems biology: proteogenomic approaches to uncover the role of proteomic variation in driving cancer

Cliff Stains, PhD
Associate Professor, Chemistry
Chemical approaches for interrogating cellular processes

Lukas Tamm, PhD
Professor, Molecular Physiology and Biological Physics
Structural biophysics of membranes proteins involved in cell signaling

Scott Vande Pol, MD, PhD
Associate Professor, Pathology
Physical structure and biological functions of papillomavirus E6 oncoproteins

Michael Weber, PhD
Professor, Microbiology, Immunology, and Cancer Biology
Mechanisms of resistance to cancer therapy driven by signal transduction adaptations

Jochen Zimmer, PhD
Professor, Molecular Physiology and Biological Physics
Structural and molecular biology of complex carbohydrate biosyntheses

Eli Zunder, PhD
Assistant Professor, Biomedical Engineering
Mechanisms that control stem cell fate