Cancer Therapeutics Program (CRX) Members

Kumari Andarawewa, DVM, MSS, PhD, DACLAM
Assistant Professor, Radiation Oncology

Immunologic effects of focused ultrasound on cancer tissues.

Karen Ballen, MD
Professor, Hematology and Oncology

Clinical trials of stem cell transplant.

Todd Bauer, MD    
Professor, Surgery

Targeted therapies for pancreatic cancer.

David Brenin, MD  
Professor, Surgery

Focused ultrasound therapy trials in breast cancer.

Kimberly Bullock, MD
Associate Professor, Surgery

Clinical trial development, immunotherapy.

Timothy Bullock, PhD
Associate Professor, Pathology
Increasing the presence and function of T cells in the tumor microenvironment; impact of CD70-CD27 co-stimulation on T cell function; function of CD4 T cells in enhancing CD8 T cell recruitment to tumors.

Mark Conaway, PhD         
Professor, Public Health Sciences

Novel clinical trials designs for targeted and immune therapies for cancer.

Lynn Dengel, MD
Assistant Professor, Surgery

Focused ultrasound and immunotherapy of melanoma.

Michael Devitt, MD
Assistant Professor, Hematology and Oncology

Clinical trials in urogenital cancers.

Patrick Dillon, MD 
Associate Professor, Hematology and Oncology

Immunotherapy of breast cancer, breast cancer clinical trials.

Robert Dreicer, MD           
Professor, Hematology and Oncology

Clinical trials of genitourinary malignancies, including immunotherapy, chemotherapy, targeted therapies, and combination therapies.

Linda Duska, MD   
Professor, Obstetrics and Gynecology

Clinical trials in ovarian cancer.

Firas El Chaer, MD
Assistant Professor, Division of Hematology and Oncology

Clinical trials in leukemias.

W. Jeffery Elias, MD
Professor, Neurosurgery

Stereotactical neurosurgery.

Michael R Elliott, PhD
Associate Professor, Microbiology, Immunology, and Cancer Biology

Understanding the function of tissue-resident macrophages as effectors of mAb-mediated cell clearance in hematologic malignancies.

Michael Engel, MD, PhD
Professor, Pediatrics

Developing new therapies for pediatric leukemias.

Victor Engelhard, PhD
Professor, Microbiology, Immunology, and Cancer Biology

T lymphocyte-based immunity to antigens expressed on melanoma and other tumors.  Identification of phosphopeptides. Elucidation of factors responsible for T cell homing to cancers.

Elizabeth Gaughan, MD  
Associate Professor, Hematology and Oncology

Clinical trials of immunotherapy for melanoma and for head and neck cancers.

Ryan Gentzler, MD
Associate Professor, Hematology and Oncology

Clinical trials of immunotherapy and combination therapies for lung cancer.

Kristen Greene, MD
Professor and Chair, Urology

Developing and testing novel imaging technologies in prostate cancer.

Alejandro Gru, MD
Associate Professor, Pathology

Pathological analysis and intraoperative immunohistochemistry.

Richard Hall, MD
Associate Professor, Hematology and Oncology
Clinical trials of lung cancer.

Jiang He, PhD
Associate Professor, Radiology and Medical Imaging
Imaging of molecular signatures.

Mark Jameson, MD, PhD, FACS
Associate Professor, Otolaryngology

Clinical trials in melanoma and head and neck cancers.

Einsley-Marie Janowski, MD, PhD
Assistant Professor, Radiation Oncology

Breast cancer; focused on investigating relevant biomarkers to evaluate treatment response and to predict for treatment related toxicity.

Kimberly Kelly, PhD
Professor, Biomedical Engineering
Targeted agents for cell surface plectin for imaging and cancer therapy.

Michael Keng, MD
Associate Professor, Hematology and Oncology

Clinical trials of hematologic malignancies.

Mark Kester, PhD  
Professor, Pharmacology

Creation and testing of nanoparticle therapies and vaccines for human cancers.

Alexander Klibanov, PhD
Associate Professor, Biomedical Engineering

Molecular imaging (primarily using ultrasound) with the intent of translation of targeted micro-bubbles for specific delineation of tumor-specific endothelial biomarkers (e.g. VEGFR2, alphVbeta3, neuropilin, VCAM-1) and drug delivery using ultrasound-triggered drug release (e.g., doxorubicin) in the tumor vasculature.

Lale Kostakoglu Shields, MD, MPH
Professor, Radiology and Medical Imaging

Imaging studies to track T cell homing after adoptive cell therapy and other immune therapies.

Paul Kunk, MD
Assistant Professor, Hematology and Oncology

Clinical trials in gastrointestinal cancers.

Charles Landen, MD
Associate Professor, Obstetrics and Gynecology
Basic discovery in cancer resistance to chemotherapy.

Tri Le, MD    
Assistant Professor, Hematology and Oncology

Clinical trials for gastrointestinal cancers

Daniel W. Lee, MD
Assistant Professor, Pediatrics

Clinical trials of CAR T cells.

Thomas P. Loughran, MD           
Professor, Hematology and Oncology

Large granular lymphocyte leukemia: oncogenic mechanisms, and clinical trials for therapy. Combination therapy for hematologic malignancies.

Lawrence G. Lum, MD, DSC      
Professor, Hematology and Oncology

Adoptive cell therapy of cancers with bispecific antibody armed T cells (BATs).

Enrica Marchi, MD, PHD
Assistant Professor, Hematology and Oncology

Mechanism and clinical trials in T cell lymphomas.

Linda Martin, MD, MPH
Associate Professor, Surgery

Clinical trials for lung cancer.

Jamie Mata, PhD
Associate Professor
, Radiology and Medical Imaging
Early detection and characterization of lung cancer using hyperpolarized gas MRI; Non-invasive surgical treatment of lung cancer using Magnetic Resonance guided Focused Ultrasound.

Ileana Mauldin, PhD         
Assistant Professor, Surgery

Immune microenvironment of cancers, and impact of immune therapy.

Trish Millard, MD   
Assistant Professor, Hematology and Oncology

Clinical trials of breast cancer.

Wilson G Miller, PhD
Associate Professor, Radiology and Medical Imaging

Development of new pulse-sequence techniques, contrast mechanisms, and hardware for magnetic resonance (MR) imaging in cancer.

Kiel Neumann, PhD          
Assistant Professor, Radiology and Medical Imaging

To develop new molecular imaging agents, which can be detected by Positron Emission Tomography (PET).

Owen O’Connor, MD, PhD
Professor, Hematology and Oncology

Mechanism and clinical trials in T cell lymphomas.

Gina Petroni, PhD 
Professor, Public Health Sciences

Clinical trials of cancer immunotherapy.

Craig Portell, MD   
Associate Professor, Hematology and Oncology

Clinical trials of combination immunotherapy and targeted therapy for hematologic malignancies.

Richard Price, PhD           
Professor, Biomedical Engineering

Focused ultrasound and drug delivery.

Matthew Reilley, MD        
Assistant Professor, Hematology and Oncology

Clinical trials in GI cancers.

Kara Romano, MD
Assistant Professor, Radiation Oncology

Radiation oncology clinical trials.

David Schiff, MD   
Professor, Neurology

Clinical trials in brain tumors.

Shayna Showalter, MD    
Associate Professor, Surgery

Precision Breast - Intraoperative Radiation Therapy (PB-IORT) Clinical Trials.

Jeffrey Siebers, PhD        
Professor, Radiation Oncology

Clinical effects of delineation and geometric uncertainties in conformal radiation therapy.

Craig Slingluff, MD
Professor, Surgery

Cancer vaccines and combination immunotherapy for melanoma, with evaluation of the cellular immune response and the tumor microenvironment.

Jogender Tushir-Singh, PhD     
Assistant Professor, Biochemistry and Molecular Genetics

Bispecific antibodies for cancer therapy.

Indumathy Varadarajan, MD
Assistant Professor, Hematology and Oncology

Bone marrow transplant and cellular immunotherapy.

Nolan Wages, PhD
Associate Professor, Public Health Sciences

Novel clinical trial designs to facilitate combination immunotherapies for human cancers.

Krishni Wijesooriya, PhD
Associate Professor, Radiation Oncology

Radiation therapy contribution to the generation of anti-tumor T cells and the negative effects of radiation therapy on circulating immune cells

Luke Wilkins, MD  
Associate Professor, Radiology and Medical Imaging

Development of novel cancer therapeutics.

Michael Williams, MD      
Professor, Hematology and Oncology

Clinical and translational research of novel therapeutics and prognostic biomarkers in hematologic malignancies, with a focus in non-Hodgkin lymphoma and chronic lymphocytic leukemia.