Mitral Valve Repair for People With Heart Failure

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Surgery can successfully treat mitral valve regurgitation. Mitral valve regurgitation is a leak in your mitral valve that causes blood to go in the wrong direction. The traditional open-heart operation closes the leaking valve in your heart. 

However, if you have both mitral valve regurgitation and heart failure, surgery to repair your mitral valve is very risky. You must rely on medication as your only treatment for tiredness, trouble breathing and other symptoms. This can be difficult. Medication by itself doesn’t always work.

MitraClip® for People With Heart Failure

At UVA, we participated in research (called the COAPT trial) that focused on finding an effective treatment for patients with both mitral valve and heart failure. The efforts were successful. We found that, using MitraClip, we can repair the leaking mitral valve in your heart with a minimally invasive procedure that does not require open-heart surgery.

This treatment:

  • Reduces shortness of breath
  • Gives you the ability to exercise
  • Improves your quality of life
  • Lessens your risk of dying from heart failure causes
  • Lowers your possibility of being hospitalized for heart failure

The Results of the COAPT MitraClip Clinical Trial

The COAPT trial evaluated the safety and effectiveness of transcatheter mitral valve repair using the MitraClip device to treat patients with heart failure and mitral regurgitation who continued to suffer despite medication.

The trial found that patients who received the MitraClip experienced:

  • No device-related complications
  • Improved physical functions
  • Reduced risks for death and hospitalization

Following this clinical trial, the procedure gained FDA approval.