UVa Health System Center for Research in Reproduction seeks adolescent girls ages 7-18 who have symptoms of high male hormone for a research study. The purpose of the study is to see how a medication, metformin, effects the adrenal and ovarian production of a group of hormones known as androgens.
You may be eligible for this study if: You have high levels of male hormone. Symptoms and signs of high male hormone include irregular menstrual periods, excess hair growth, and/or high testosterone levels. Participants must not have taken contraceptive pills or hormonal medications for 3 months prior to the study.
Study involves approximately 7 study visits. Option ‘A’ has 5 outpatient visits and 2 inpatient admissions. Option ‘B’ has 7 outpatient visits. All visits will be at the Clinical Research Unit (CRU). Inpatient admission will last 16 hours each. The study will include blood draws. Volunteers will take metformin for three months as part of study procedures.
Study-related exams, tests and medications are provided free of charge. For more information please contact firstname.lastname@example.org
Compensation for study completion is $500 in gift cards