Phase 1/2 Multicenter, Open-Label Study of CTX-712 in Patients with Relapsed/Refractory Acute Myeloid Leukemia and Higher Risk Myelodysplastic Syndromes

UVA Tracking #
301402
Principal Investigator
Daniel R Reed
Contact
Contact Phone
Official Trial Title
Phase 1/2 Multicenter, Open-Label Study of CTX-712 in Patients with Relapsed/Refractory Acute Myeloid Leukemia and Higher Risk Myelodysplastic Syndromes
Study Description

The University of Virginia is participating in a clinical research study for adults ages 18 and over, who have been diagnosed with a blood cancer, including Acute Myeloid Leukemia (AML) and Higher Risk Myelodysplastic Syndromes (MDS), which has returned after treatment or does not respond to treatment. This study is investigating the safety and effectiveness of a new experimental drug, CTX-712, in patients with blood cancers, including AML and higher risk MDS and to find out what effects, good and/or bad, it has on you and your disease.

You can continue to receive CTX-712 for up to 2 years as long as your cancer is responding to the treatment, or until your disease gets worse (unless otherwise decided by your study doctor), you experience unacceptable side effects, you withdraw your consent, you start a different anticancer treatment, the study doctor believes you are no longer receiving benefit from the study drug, or any other discontinuation criteria occur.

Study-related procedures that are being done beyond your standard of care will be provided at no cost to you or your insurance.

Additional information can be found here: https://clinicaltrials.gov/study/NCT05732103

uvacancertrials@hscmail.mcc.virginia.edu

The (department, division name) seeks (insert as applies: adults/men/women/adolescents/children) ages (insert) with (insert condition) for a research study. The purpose of the study is (insert purpose of study - eg.to test the effectiveness of an investigational medicine; or to find out how stress effects blood pressure.)

(Optional)You may be eligible for this study if: (insert brief eligibility criteria 3 or 4 top criteria and in lay language. Do not copy eligibility criteria from the protocol)

Study involves (insert procedures-examples: taking an experimental medicine/placebo, blood draws, x rays, overnight stays,) (Insert x number of visits every x (weeks, months,) each visit lasting x amount of time or give range).

Insert one of the following:
Study-related (insert exams, tests and experimental medication) provided at no cost.
or
Participant’s insurance company will be billed for medication, test,s and procedures

Compensation

No Compensation