Radiation treatment research study for adults with prostate cancer

UVA Tracking #
Principal Investigator
Christopher Luminais
Songserea Wood
Contact Phone
Official Trial Title
Prospective trial of combination external beam radiation therapy and MRI-guided, dose-differentiated high dose-rate prostate brachytherapy boost for unfavorable-intermediate, high, and very high-risk prostate cancer
Study Description

The Department of Radiation Oncology seeks men ages 18 and older with prostate cancer for a research study. The purpose of the study is to test whether a combination of Androgen deprivation therapy (ADT), MRI guided high dose radiation (HDR) brachytherapy treatment and external beam radiation therapy (EBRT) treatments lead to less side effects than similar treatments that don’t use an MRI during brachytherapy. This study is also looking at patient outcomes, quality of life and overall survival for patients receiving this treatment.

You may be eligible for this study if you have been diagnosed with unfavorable intermediate, high, or very high risk prostate cancer and plan on receiving radiation therapy for definitive treatment.

This study involves receiving one dose of brachytherapy and 5 weeks of EBRT with or without ADT. Participants will be asked to complete questionnaires on sexual function, urinary and bowel symptoms during treatment and follow up visits. Clinic follow ups will occur 3 months and annually after radiation treatment.
Study-related questionnaires will be provided at no cost.


No Compensation

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