Reproductive Hormone Studies

IRB/UVA Tracking #
Principal Investigator
Christopher McCartney
Melissa Gilrain
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Contact Phone
Official Trial Title
Relative desirability of metformin vs. birth control pills in treating PCOS in women of later reproductive age.
Study Description

UVa Health System Center for Research in Reproduction seeks female volunteers with Polycystic Ovary Syndrome (PCOS), ages 40 to 47, for a research study. The purpose of the study is to learn if metformin is as effective as birth control pills for health-related quality of life.

You may be eligible for this study if: You have PCOS. Symptoms and signs include irregular menstrual periods, excess hair growth, and high testosterone levels. Participants must not have taken contraceptive pills or hormonal medications for 3 months prior to the study.

Study involves 7 outpatient visits, taking metformin or birth control pills, blood draws, saliva collection, transvaginal ultrasound, and questionnaires.

Study-related exams, tests and medications are provided free of charge. For more information, please contact


Compensation for study completion is $480