The Division of Asthma, Allergy, and Immunology seeks 18-40 year old non-smoking adults for a common cold research study. To be eligible, you must have allergies and asthma that is well controlled. Screening involves 2 visits each lasting 1 to 1 ½ hours. Visits include questionnaires, blood draws, lung function (breathing) tests, allergy skin testing, and pregnancy testing for females.
Based on the screening results, participants may be eligible for a study to look at how the immune system responds after being treated with the study medication, Dupilumab or placebo, before being exposed to an experimental cold virus. This study will require exposure to an experimental cold virus with 13 study visits over 14 weeks (including the 2 screening visits). Visits include nasal samples, lung function (breathing) tests, brief physical exams, blood draws, completion of diary cards, questionnaires, and pregnancy testing for females.
All study related tests are provided free of charge.
Participants will be compensated up to $1000 for their time.