Adventitial Cystic Disease

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Adventitial cystic disease is a rare disease that occurs when a cyst filled with a mucus-like substance forms in one of the arteries, most commonly in the popliteal artery, which supplies blood to the knee joint and thigh and calf muscles. The cyst can narrow or block the affected artery.

Symptoms of Adventitial Cystic Disease

The disease is most likely to occur in young and middle-aged men.

You may have adventitial cystic disease if you experience:

  • Sudden calf cramps
  • Leg pain

Diagnosis & Treatment at UVA

At UVA, we can diagnose you by using these tests:

  • Computed tomography angiography (CTA)
  • Physical exam
  • Ultrasound imaging

The most common treatment for adventitial cystic disease is surgery. If the cyst has caused a complete blockage, your surgeon may remove the cyst and reconstruct the blocked portion of the artery, often by using a blood vessel from elsewhere in the body.


Content was created using EBSCO’s Health Library. Edits to original content made by Rector and Visitors of the University of Virginia. This information is not a substitute for professional medical advice.