Looking for adults aged 18-55 to complete a research study about exercise

The Department of Kinesiology seeks adult men and women ages 18-55 for a research study. The purpose of the study is to see how exercise effects the stomach hormone, ghrelin.

You may be eligible for this study if you have normal weight body mass index, have an obese body mass index, have normal blood sugar levels, or have abnormal blood sugar levels (prediabetes).

A phase 2, open-label, single-arm, multicohort, multicenter trial to evaluate the efficacy and safety of JCAR017 in adult subjects with relapsed or refractory indolent B-cell non-hodgkin lymphoma (NHL)

The University of Virginia Cancer Center seeks participants 18 years old or above to participate in a study that looks at a new treatment for follicular or marginal zone lymphoma that has not responded to or returned after previous treatments. The JCAR-017 treatment works on the T-cells in the body (part of the immune system).

Participation on this study involves up to 26 weeks. Participants are also required to take part in a 15-year long-term follow up study. Study-related tests and procedures and study drug will be covered by the study sponsor.

Phase II Randomized Study of Neoadjuvant Pembrolizumab Alone or in Combination with CMP-001 in Patients with Operable Melanoma: Efficacy and Biomarker Study

The University of Virginia is conducting a clinical research study for adults ages 18 and over, who have advanced melanoma that is still considered resectable by surgery. This study is being done to answer the following question:

Research Study for those with Subcortical Epilepsy

The purpose of the feasibility (early stage) study is to evaluate the effectiveness and safety of an investigational device used to treat seizures that are not well controlled by medication and are due to a small growth of abnormal cells in the middle of the brain, most commonly hypothalamic hamartomas, subcortical nodules, or tuberous sclerosis. The device sends ultrasound waves into the abnormal area of the brain and ablates (or kills) the cells that may be causing epilepsy.

Patients with allogeneic hematopoietic cell transplants are needed for a study to research an investigative cellular therapy to prevent life threatening viral infections compared to a placebo

The University of Virginia Cancer Center is conducting a clinical research study for patients who are adults ages 18 and over, and have allogeneic hematopoietic cell transplants. The purpose of this study to evaluate an investigational drug (Viralym-M) versus a placebo in patients with allogeneic hematopoietic cell transplants and may develop viral infections. The effects of the investigational drug will be evaluated for this study.

Study For Patients With Newly Diagnosed Acute Myeloid Leukemia To See If Drugs for Treating Heart Problems May Help To Prevent Heart Problems

The University of Virginia Cancer Center is conducting a clinical research study for patients with newly diagnosed acute myeloid leukemia (AML). One of the drugs used in the standard treatment for AML can increase risk of damage to the heart. Beta blockers and angiotensin-converting enzyme inhibitors (ACE inhibitors) are used to treat people who have this kind of damage to the heart. These drugs are taken orally (pills taken by mouth).

Research Study for healthy adults with a risk of developing Alzheimer’s Disease

We are currently recruiting healthy adults for a research study on the prevention of Alzheimer's Disease (AD).
The study will take place over 2 years and require participants to take an investigational medication every day.
During the two years we will collect information about your medical history, family history, cognitive status and
mood.
We will also collect images of your brain and collect blood to determine if you have a genetic risk factor for AD.

Study for Patients Planning to Undergo Abdominal Surgery for Colorectal, Hepatobiliary, or Gynecologic Cancer

The University of Virginia Cancer Center is conducting a clinical research study for patients undergoing surgery for colorectal, hepatobiliary, or gynecologic cancer. Studies have shown that people who are more physically fit before surgery do better after surgery. The purpose of this study is to test two physical activity interventions and a “control” group to make sure that participants can do the interventions and also to see if there are changes in activity and fitness in each group.

Study for Patients with Peripheral T-Cell Lymphoma (PTCL) or Cutaneous T-Cell Lymphoma (CTCL) Comparing an Investigational Combination of Pembrolizumab (Keytruda) with Decitabine and/or Pralatrexate (PTCL 002)

The University of Virginia Cancer Center is conducting a clinical research study for patients who are adults with peripheral T-cell lymphoma (PTCL) or cutaneous T-cell lymphoma (CTCL) who have received treatment but the treatment either didn’t work or stopped working. The purpose of this study is to better understand the safety and efficacy of the combinations of pembrolizumab with decitabine, pralatrexate, or both decitabine and pralatrexate.

Study for Patients with High Risk Leukemias or Myelodysplastic Syndrome to Start Supportive Care Earlier in the Treatment Regimen

The University of Virginia Cancer Center is conducting a clinical research study for patients who are adults with either acute leukemia or myelodysplastic syndrome (MDS) who are either over age 65 OR have received treatment but the treatment either didn’t work or stopped working. The purpose of this study is to estimate the potential benefit of early and continued palliative care consultation in this population.

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