Ewing's Sarcoma

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Ewing's sarcoma is a cancerous bone tumor that can occur in any bone in the body. When it occurs in soft tissue, it is called extraosseous sarcoma. The most commonly affected areas include the pelvis, thigh, lower leg, upper arm, and chest wall.

How We Treat Ewing's Sarcoma

Treatment involves a combination of chemotherapy, surgery and radiation. Typically, we start with chemotherapy for 8-12 weeks. We then evaluate the tumor with a CT or MRI scan. Depending on the tumor size and location, either surgery or radiation follows. Chemotherapy then resumes for several months after surgery or radiation.

Who Treats This Type of Bone Cancer?

The team that typically cares for you with this cancer includes:

  • A cancer specialist or oncologist
  • An orthopedic surgeon who operates on bones
  • A radiation oncologist who works with radiation to kill cancer cells

Signs of Ewing's Sarcoma

Symptoms include:

  • Pain, redness, and swelling surrounding the tumor
  • Fever
  • Weight loss and reduced appetite
  • Fatigue
  • Paralysis and incontinence in cases where the tumor is near the spinal cord
  • Numbness, tingling, and paralysis caused by compression of nerves by the tumor
  • Difficulty breathing if the tumor is in the chest wall

Bone Cancer in Young Adults

Ewing’s sarcoma most commonly affects the pelvis, thigh, leg, arm and chest wall. Gregory Domson, MD, explains treatment and care at UVA. View Ewing's sarcoma transcript.

Testing for Bone Cancer
bone biopsy
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We use advanced imaging to look at the structures of your body: 

  • X-rays
  • Bone scans
  • CT scan
  • MRI scan
  • PET/CT scan — to evaluate the metabolic activity of tissue

We'll also test your body fluids and tissues with:

  • Blood tests
  • Biopsy


Content was created using EBSCO’s Health Library. Edits to original content made by Rector and Visitors of the University of Virginia. This information is not a substitute for professional medical advice.